An efficient synthesis of pyrimidines and pyridines has been developed from readily
available aromatic ketones, aldehydes and ammonium salts under transition-metal-free …

An efficient method for the modular synthesis of various pyrimidine derivatives by means of
the reactions of ketones, aldehydes, or esters with amidines in the presence of an in situ …

A new set of 2-(2-benzimidazolyl) pyridine ligand based air and moisture stable ruthenium
complexes were synthesized and characterized. The catalytic behaviors of these complexes …

Pyrimidine heterocycles are proven to be biologically active heterocycles, found in many
biological systems, displaying a broad spectrum of biological activities including anticancer …

An efficient defluorinative net-[3+ 3]-cyclization strategy for the construction of perfluoroalkyl-
substituted pyrimidine derivatives by using a series of perfluoroalkyl alkynes and amidines …

An efficient copper-catalyzed three-component cyclization for the construction of highly
functionalized pyrimidine derivatives from readily available amidines, styrenes and …

Various polysubstituted pyrimidines are smoothly formed via a base-promoted
intermolecular oxidation C–N bond formation of allylic C (sp3)–H and vinylic C (sp2)–H of …

Triflic acid (10 mol%) catalyzes the highly regioselective [2+ 2+ 2] cycloaddition between two
cyanamides and one ynamide to grant the 2, 4, 6-triaminopyrimidine core. The developed …

An efficient copper-catalyzed one-pot three-component reaction of amidines, primary
alcohols and secondary alcohols has been developed to synthesize multisubstituted …

Drugs against malaria are losing their effectiveness because of emerging drug resistance.
This underscores the need for novel therapeutic options for malaria with mechanism of …