Nox, reactive oxygen species and regulation of vascular cell fate
D Burtenshaw, R Hakimjavadi, EM Redmond… - Antioxidants, 2017 - mdpi.com
The generation of reactive oxygen species (ROS) and an imbalance of antioxidant defence
mechanisms can result in oxidative stress. Several pro-atherogenic stimuli that promote …
mechanisms can result in oxidative stress. Several pro-atherogenic stimuli that promote …
Bioreactors for cardiac tissue engineering
The advances in biotechnology, biomechanics, and biomaterials can be used to develop
organ models that aim to accurately emulate their natural counterparts. Heart disease, one …
organ models that aim to accurately emulate their natural counterparts. Heart disease, one …
Experimental and theoretical analyses of the age-dependent large-strain behavior of Sylgard 184 (10: 1) silicone elastomer
The commercial polydimethysiloxane elastomer Sylgard® 184 with mixing ratio 10: 1 is in
wide use for biomedical research or fundamental studies of mechanobiology. In this paper, a …
wide use for biomedical research or fundamental studies of mechanobiology. In this paper, a …
Regulation of mesenchymal stem cell 3D microenvironment: From macro to microfluidic bioreactors
Human mesenchymal stem cells (hMSCs) have emerged as an important cell type in cell
therapy and tissue engineering. In these applications, maintaining the therapeutic properties …
therapy and tissue engineering. In these applications, maintaining the therapeutic properties …
Biomechanical regulation of mesenchymal stem cells for cardiovascular tissue engineering
Mesenchymal stem cells (MSCs) are an appealing potential therapy for vascular diseases;
however, many challenges remain in their clinical translation. While the use of biochemical …
however, many challenges remain in their clinical translation. While the use of biochemical …
Substrate topography interacts with substrate stiffness and culture time to regulate mechanical properties and smooth muscle differentiation of mesenchymal stem …
Substrate stiffness and topography are two powerful means by which mesenchymal stem
cells (MSCs) activities can be modulated. The effects of substrate stiffness on the MSCs …
cells (MSCs) activities can be modulated. The effects of substrate stiffness on the MSCs …
Equiaxial strain modulates adipose-derived stem cell differentiation within 3D biphasic scaffolds towards annulus fibrosus
Recurrence of intervertebral disc (IVD) herniation is the most important factor leading to
chronic low back pain and subsequent disability after discectomy. Efficacious annulus …
chronic low back pain and subsequent disability after discectomy. Efficacious annulus …
Mechanical stretch inhibits mesenchymal stem cell adipogenic differentiation through TGFβ1/Smad2 signaling
R Li, L Liang, Y Dou, Z Huang, H Mo, Y Wang… - Journal of …, 2015 - Elsevier
Mesenchymal stem cells (MSCs) are the common precursors of several functionally
disparate cell lineages. A plethora of chemical and physical stimuli contribute to lineage …
disparate cell lineages. A plethora of chemical and physical stimuli contribute to lineage …
A review of the three-dimensional cell culture technique: Approaches, advantages and applications
W Zhang, A Zhuang, P Gu, H Zhou… - Current stem cell …, 2016 - ingentaconnect.com
Cell culture is a core and basic technique in biotechnology and is widely applied in biology,
medicine, drug research and development. Traditional two-dimensional cell culture methods …
medicine, drug research and development. Traditional two-dimensional cell culture methods …
Strain and vibration in mesenchymal stem cells
B McClarren, R Olabisi - International Journal of Biomaterials, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into any
mesenchymal tissue, including bone, cartilage, muscle, and fat. MSC differentiation can be …
mesenchymal tissue, including bone, cartilage, muscle, and fat. MSC differentiation can be …