Lipid nanoparticle technologies for nucleic acid delivery: A nanoarchitectonics perspective
Lipid‐based nanoparticles have emerged as a clinically viable platform technology to
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …
Multifunctional delivery systems for peptide nucleic acids
The number of applications of peptide nucleic acids (PNAs)—oligonucleotide analogs with a
polyamide backbone—is continuously increasing in both in vitro and cellular systems and …
polyamide backbone—is continuously increasing in both in vitro and cellular systems and …
Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy
Glioblastoma (GBM) is one of the most lethal malignancies with poor survival and high
recurrence rates. Here, we aimed to simultaneously target oncomiRs 10b and 21, reported …
recurrence rates. Here, we aimed to simultaneously target oncomiRs 10b and 21, reported …
Development of surface chemical strategies for synthesizing redox‐responsive diatomite nanoparticles as a green platform for on‐demand intracellular release of an …
Redox‐responsive silica drug delivery systems are synthesized by aeco‐friendly diatomite
source to achieve on‐demand release of peptide nucleic acid (PNA) in tumor reducing …
source to achieve on‐demand release of peptide nucleic acid (PNA) in tumor reducing …
Next generation miRNA inhibition using short anti-seed PNAs encapsulated in PLGA nanoparticles
Selective inhibition of microRNAs (miRNAs) offers a new avenue for cancer therapeutics.
While most of the current anti-miRNA (antimiR) reagents target full length miRNAs, here we …
While most of the current anti-miRNA (antimiR) reagents target full length miRNAs, here we …
Next-generation poly-L-histidine formulations for miRNA mimic delivery
Many diseases, especially cancer, are caused by the abnormal expression of non-coding
microRNAs (miRNAs), which regulate gene expression, leading to the development of …
microRNAs (miRNAs), which regulate gene expression, leading to the development of …
Aggregation‐Enhanced Photoluminescence and Photoacoustics of Atomically Precise Gold Nanoclusters in Lipid Nanodiscs (NANO2)
A Tahmasbi Rad, Y Bao, HS Jang, Y **a… - Advanced functional …, 2021 - Wiley Online Library
The authors designed a structurally stable nano‐in‐nano (NANO2) system highly capable of
bioimaging via an aggregation‐enhanced NIR excited emission and photoacoustic …
bioimaging via an aggregation‐enhanced NIR excited emission and photoacoustic …
Effect of drug-to-lipid ratio on nanodisc-based tenofovir drug delivery to the brain for HIV-1 infection
Background: Combination antiretroviral therapy has significantly advanced HIV-1 infection
treatment. However, HIV-1 remains persistent in the brain; the inaccessibility of the blood …
treatment. However, HIV-1 remains persistent in the brain; the inaccessibility of the blood …
Peptide nucleic acids and their role in gene regulation and editing
The unique properties of peptide nucleic acid (PNA) makes it a desirable candidate to be
used in therapeutic and biotechnological interventions. It has been broadly utilized for …
used in therapeutic and biotechnological interventions. It has been broadly utilized for …
Modulation of DNA and RNA by PNA
P Muangkaew, T Vilaivan - Bioorganic & Medicinal Chemistry Letters, 2020 - Elsevier
Peptide nucleic acid (PNA), a synthetic DNA mimic that is devoid of the (deoxy) ribose-
phosphate backbone yet still perfectly retains the ability to recognize natural nucleic acids in …
phosphate backbone yet still perfectly retains the ability to recognize natural nucleic acids in …