Benzodiazepines remain important therapeutic options in psychiatric practice

SL Dubovsky, D Marshall - Psychotherapy and Psychosomatics, 2022 - karger.com
Benzodiazepines and medications acting on benzodiazepine receptors that do not have a
benzodiazepine structure (z-drugs) have been viewed by some experts and regulatory …

Results of the European Group for the Study of Resistant Depression (GSRD)—basis for further research and clinical practice

L Bartova, M Dold, A Kautzky, C Fabbri… - The World Journal of …, 2019 - Taylor & Francis
Objectives: The overview outlines two decades of research from the European Group for the
Study of Resistant Depression (GSRD) that fundamentally impacted evidence-based …

Clinical factors predicting treatment resistant depression: affirmative results from the European multicenter study

A Kautzky, M Dold, L Bartova, M Spies… - Acta Psychiatrica …, 2019 - Wiley Online Library
Objectives Clinical variables were investigated in the 'treatment resistant depression (TRD)‐
III'sample to replicate earlier findings by the European research consortium 'Group for the …

Practical recommendations for the management of treatment-resistant depression with esketamine nasal spray therapy: basic science, evidence-based knowledge …

S Kasper, WJ Cubała, A Fagiolini… - The World Journal of …, 2021 - Taylor & Francis
Objectives Despite the available therapies for treatment-resistant depression (TRD), there
are a limited number that are evidence-based and effective in this hard-to-treat population …

Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samples

C Fabbri, S Kasper, A Kautzky, L Bartova… - The British Journal of …, 2019 - cambridge.org
BackgroundTreatment-resistant depression (TRD) is the most problematic outcome of
depression in terms of functional impairment, suicidal thoughts and decline in physical …

Higher polygenic risk scores for schizophrenia may be suggestive of treatment non-response in major depressive disorder

G Fanelli, F Benedetti, S Kasper, J Zohar… - Progress in Neuro …, 2021 - Elsevier
Up to 60% of patients with major depressive disorder (MDD) do not respond to the first
treatment with antidepressants. Response to antidepressants is a polygenic trait, although …

Temperament and character influence on depression treatment outcome

M Balestri, S Porcelli, D Souery, S Kasper… - Journal of affective …, 2019 - Elsevier
Background: personality features have been repeatedly associated with depression
treatment outcome in Major Depressive Disorder (MDD), however conclusive results are still …

A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genoty**

C Fabbri, S Kasper, A Kautzky, J Zohar… - Translational …, 2020 - nature.com
Abstract Treatment-resistant depression (TRD) occurs in~ 30% of patients with major
depressive disorder (MDD) but the genetics of TRD was previously poorly investigated …

7T ultra-high-field neuroimaging for mental health: an emerging tool for precision psychiatry?

I Neuner, T Veselinović, S Ramkiran… - Translational …, 2022 - nature.com
Given the huge symptom diversity and complexity of mental disorders, an individual
approach is the most promising avenue for clinical transfer and the establishment of …

Sex‐related effects in major depressive disorder: Results of the European Group for the Study of Resistant Depression

L Bartova, M Dold, G Fugger, A Kautzky… - Depression and …, 2021 - Wiley Online Library
Background Sex‐related effects on the evolution and phenotype of major depressive
disorder (MDD) were reported previously. Methods This European multicenter cross …