Ultrasound nanotheranostics: Toward precision medicine

Y Qin, X Geng, Y Sun, Y Zhao, W Chai, X Wang… - Journal of Controlled …, 2023 - Elsevier
Ultrasound (US) is a mechanical wave that can penetrate biological tissues and trigger
complex bioeffects. The mechanisms of US in different diagnosis and treatment are different …

Review of robot-assisted HIFU therapy

A Gunderman, R Montayre, A Ranjan, Y Chen - Sensors, 2023 - mdpi.com
This paper provides an overview of current robot-assisted high-intensity focused ultrasound
(HIFU) systems for image-guided therapies. HIFU is a minimally invasive technique that …

HIF-1α is a rational target for future ovarian cancer therapies

X Wang, Z Du, T Xu, X Wang, W Li, J Gao, J Li… - Frontiers in …, 2021 - frontiersin.org
Ovarian cancer is the eighth most commonly diagnosed cancer among women worldwide.
Even with the development of novel drugs, nearly one-half of the patients with ovarian …

[HTML][HTML] 2D spatiotemporal passive cavitation imaging and evaluation during ultrasound thrombolysis based on diagnostic ultrasound platform

Q Zhang, Y Zhu, G Zhang, H Xue, B Ding, J Tu… - Ultrasonics …, 2024 - Elsevier
Acoustic cavitation plays a critical role in various biomedical applications. However,
uncontrolled cavitation can lead to undesired damage to healthy tissues. Therefore, real …

An affordable and easy-to-use focused ultrasound device for noninvasive and high precision drug delivery to the mouse brain

Z Hu, S Chen, Y Yang, Y Gong… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Objective: Focused ultrasound (FUS) combined with microbubble-mediated blood-brain
barrier (BBB) opening (FUS-BBBO) is not only a promising technique for clinical applications …

An efficient and multi-focal focused ultrasound technique for harmonic motion imaging

N Saharkhiz, HAS Kamimura… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Harmonic motion imaging (HMI) is an ultrasound-based elasticity imaging technique that
utilizes oscillatory acoustic radiation force to estimate the mechanical properties of tissues …

Image-guided focused ultrasound-mediated molecular delivery to breast cancer in an animal model

R Margolis, L Basavarajappa, J Li… - Physics in Medicine & …, 2023 - iopscience.iop.org
Tumors become inoperable due to their size or location, making neoadjuvant chemotherapy
the primary treatment. However, target tissue accumulation of anticancer agents is limited by …

Identification of Ultrasound‐Sensitive Prognostic Markers of LAML and Construction of Prognostic Risk Model Based on WGCNA

C Tian, H Guo, W Wei - Journal of Oncology, 2023 - Wiley Online Library
Background. Acute myeloid leukemia (LAML) is the most widely known acute leukemia in
adults. Chemotherapy is the main treatment method, but eventually many individuals who …

Hepatotoxicity of nanomaterials: From mechanism to therapeutic strategy

C Gao, M Wang, Y Zheng, L Zhang, J He… - Nanotechnology …, 2024 - degruyter.com
Most nanoparticles are metabolized and accumulated in the liver; therefore, this review,
based on most data collected from PubMed. gov between 2012 and 2023 with the keywords …

Ultrasound image-guided drug delivery using a spherically focused phased array transducer

R Margolis, L Basavarajappa, J Li… - 2021 IEEE International …, 2021 - ieeexplore.ieee.org
The tumor microenvironment presents a physical barrier for successful drug delivery. Low-
intensity pulsed ultrasound (US) in combination with a microbubble (MB) contrast agent has …