Background There are concerns that the response to the COVID-19 pandemic in the UK
might have worsened physical and mental health, and reduced use of health services …

Rationale Clinical trials are the gold standard for testing interventions. COVID-19 has further
raised their public profile and emphasised the need to deliver better, faster, more efficient …

Background Studies have shown that chronic obstructive pulmonary disease (COPD)
exacerbation events are related to future events; however, previous literature typically …

Background Discrepancy exists amongst studies investigating the effect of comorbid heart
failure (HF) on the morbidity and mortality of chronic obstructive pulmonary disease (COPD) …

Background Early descriptions of patients admitted to hospital during the COVID-19
pandemic showed a lower prevalence of asthma and chronic obstructive pulmonary disease …

Background The COVID-19 pandemic and ensuing national lockdowns have dramatically
changed the healthcare landscape. The pandemic's impact on people with chronic …

Rationale: Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are
important adverse events in the natural history of chronic obstructive pulmonary disease …

Rationale: Cardiovascular events after chronic obstructive pulmonary disease (COPD)
exacerbations are recognized. Studies to date have been post hoc analyses of trials, did not …

Objective To determine whether the use of glucagon-like peptide 1 (GLP-1) receptor
agonists, dipeptidyl peptidase 4 (DPP-4) inhibitors, and sodium-glucose co-transporter-2 …

Background In recent years, the development and application of emerging information
technologies, such as artificial intelligence, cloud computing, Internet of Things, and …