Recent development of improved tools and methods to analyse tissues at the three-
dimensional level has expanded our capacity to investigate morphogenesis of foetal liver …

The zebrafish research community is celebrating! The zebrafish genome has recently been
sequenced, the Zebrafish Mutation Project (launched by the Wellcome Trust Sanger …

A critical shortage of donor organs for treating end-stage organ failure highlights the urgent
need for generating organs from human induced pluripotent stem cells (iPSCs). Despite …

Lipid nanoparticles (LNPs) are the leading nonviral technologies for the delivery of
exogenous RNA to target cells in vivo. As systemic delivery platforms, these technologies …

Fluorescence correlation spectroscopy (FCS) is a single molecule sensitive tool for the
quantitative measurement of biomolecular dynamics and interactions. Improvements in …

Defined genetic models based on human pluripotent stem cells have opened new avenues
for understanding disease mechanisms and drug screening. Many of these models assume …

The zebrafish has emerged as a powerful vertebrate model for studying liver‐associated
disorders. Liver damage is a crucial problem in the process of drug development and …

Hepatic hydrothorax (HH) is the presence of pleural effusion in a patient with cirrhosis
without evidence of other cardiopulmonary disease. It occurs in 5%-15% of patients with …

There is significant overlap in the genes and pathways that control liver development and
those that regulate liver regeneration, hepatic progenitor cell expansion, response to injury …