Octahedral Ir (III) complexes bearing cyclometalated ligands exhibit a great stability in
biological media and are excellent therapeutical and phototherapeutical candidates for …

The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Metallodrugs offer potential for unique mechanisms of drug action based on the choice of
the metal, its oxidation state, the types and number of coordinated ligands and the …

Conspectus Iridium is a relatively rare precious heavy metal, only slightly less dense than
osmium. Researchers have long recognized the catalytic properties of square-planar IrI …

Despite encouraging results from preliminary studies of anticancer therapies, the lack of
tumor specificity remains an important issue in the modern pharmaceutical industry. New …

The clinical success of cisplatin and its derivatives has had an enormous impact on the
discovery of novel metal-based drugs. Extensive studies have focused on the interaction of …

Possessing important advantages over conventional one-photon excited emission such as
great depth discrimination and reduced photo-damage, two-photon excited emission (TPE) …

Investigation on the interactions between enantiomers of chiral drugs and biomolecules can
help precisely understand their biological behaviors in vivo and provide insights into the …

Biomedical investigations reveal that excessive formaldehyde generation is possibly a
critical factor for tissue cancerization, cancer progression, and metastasis. Responsive …

Group 9 metal complexes based on iridium and rhodium have recently arisen as fascinating
potential alternatives to existing platinum and ruthenium metallodrugs. While long regarded …