The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy
D Bruni, HK Angell, J Galon - Nature Reviews Cancer, 2020 - nature.com
Abstract The international American Joint Committee on Cancer/Union for International
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …
The immune contexture in cancer prognosis and treatment
Immunotherapy is currently the most rapidly advancing area of clinical oncology, and
provides the unprecedented opportunity to effectively treat, and even cure, several …
provides the unprecedented opportunity to effectively treat, and even cure, several …
Consensus guidelines for the detection of immunogenic cell death
Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …
Cell death and immunity in cancer: from danger signals to mimicry of pathogen defense responses
AD Garg, P Agostinis - Immunological reviews, 2017 - Wiley Online Library
The immunogenicity of cancer cells is an emerging determinant of anti‐cancer
immunotherapy. Beyond develo** immunostimulatory regimens like dendritic cell‐based …
immunotherapy. Beyond develo** immunostimulatory regimens like dendritic cell‐based …
[HTML][HTML] CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer
T follicular helper cells (T FH cells) are important regulators of antigen-specific B cell
responses. The B cell chemoattractant CXCL13 has recently been linked with T FH cell …
responses. The B cell chemoattractant CXCL13 has recently been linked with T FH cell …
Natural and therapy-induced immunosurveillance in breast cancer
The immunosurveillance theory postulates that tumors evolve and progress in an
uncontrolled fashion only when anticancer immune responses fail. Natural …
uncontrolled fashion only when anticancer immune responses fail. Natural …
Molecular and translational classifications of DAMPs in immunogenic cell death
The immunogenicity of malignant cells has recently been acknowledged as a critical
determinant of efficacy in cancer therapy. Thus, besides develo** direct …
determinant of efficacy in cancer therapy. Thus, besides develo** direct …
Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian …
The emerging role of the cancer cell-immune cell interface in sha** tumorigenesis/
anticancer immunotherapy has increased the need to identify prognostic biomarkers …
anticancer immunotherapy has increased the need to identify prognostic biomarkers …
Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis
Cancer immunotherapy is revolutionizing the clinical management of several tumors, but
has demonstrated limited activity in breast cancer. The development of more effective …
has demonstrated limited activity in breast cancer. The development of more effective …
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy
S Gnjatic, V Bronte, LR Brunet, MO Butler… - … for immunotherapy of …, 2017 - Springer
As cancer strikes, individuals vary not only in terms of factors that contribute to its occurrence
and development, but as importantly, in their capacity to respond to treatment. While exciting …
and development, but as importantly, in their capacity to respond to treatment. While exciting …