The size of a cell is determined by a combination of synthesis, self-assembly, incoming
matter and the balance of mechanical forces. Such processes operate at the single-cell …

Evolutionarily divergent bacteria share a common phenomenological strategy for cell-size
homeostasis under steady-state conditions. In the presence of inherent physiological …

Escherichia coli coordinates replication and division cycles by initiating replication at a
narrow range of cell sizes. By tracking replisomes in individual cells through thousands of …

Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions
via changes in cell morphologies and macromolecular composition. How bacterial …

Growth laws emerging from studies of cell populations provide essential constraints on the
global mechanisms that coordinate cell growth,–. The foundation of bacterial cell cycle …

How cells regulate their cell cycles is a central question for cell biology. Models of cell size
homeostasis have been proposed for bacteria, archaea, yeast, plant, and mammalian cells …

It has long been known that bacteria coordinate their physiology with their nutrient
environment, yet our current understanding offers little intuition for how bacteria respond to …

Cells adopt a size that is optimal for their function, and pushing them beyond this limit can
cause cell aging and death by senescence or reduce proliferative potential. However, by …

Escherichia coli cell cycle features two critical cell-cycle checkpoints: initiation of replication
and the onset of constriction. While the initiation of DNA replication has been extensively …

Living cells proliferate by completing and coordinating two cycles, a division cycle
controlling cell size and a DNA replication cycle controlling the number of chromosomal …