PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

JS Suk, Q Xu, N Kim, J Hanes, LM Ensign - Advanced drug delivery reviews, 2016 - Elsevier
Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

P Grossen, D Witzigmann, S Sieber… - Journal of Controlled …, 2017 - Elsevier
The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Hyaluronic acid for anticancer drug and nucleic acid delivery

F Dosio, S Arpicco, B Stella, E Fattal - Advanced drug delivery reviews, 2016 - Elsevier
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …

Physicochemical properties of nanomaterials: implication in associated toxic manifestations

MA Gatoo, S Naseem, MY Arfat… - BioMed research …, 2014 - Wiley Online Library
Nanotechnology has emerged as one of the leading fields of the science having tremendous
application in diverse disciplines. As nanomaterials are increasingly becoming part of …

Application of semiconductor quantum dots in bioimaging and biosensing

IV Martynenko, AP Litvin, F Purcell-Milton… - Journal of Materials …, 2017 - pubs.rsc.org
In this review we present new concepts and recent progress in the application of
semiconductor quantum dots (QD) as labels in two important areas of biology, bioimaging …

Insights into active targeting of nanoparticles in drug delivery: advances in clinical studies and design considerations for cancer nanomedicine

AK Pearce, RK O'Reilly - Bioconjugate chemistry, 2019 - ACS Publications
Nanomedicine is a promising strategy for improving clinical outcomes for cancer therapies,
by improving drug efficacy through enhanced delivery to disease sites. It is of importance for …

Magnetic nanoparticles: essential factors for sustainable environmental applications

SCN Tang, IMC Lo - Water research, 2013 - Elsevier
In recent years, there has been an increasing use of engineered magnetic nanoparticles for
remediation and water treatments, leading to elevated public concerns. To this end, it is …

Modified hyaluronic acid based materials for biomedical applications

S Tiwari, P Bahadur - International journal of biological macromolecules, 2019 - Elsevier
Hyaluronic acid (HA) is a high molecular weight, non-sulfated anionic polysaccharide from
glycosamine glycan family. It is a versatile biomaterial that binds to specific cell receptor …

Nanoparticle PEGylation for imaging and therapy

JV Jokerst, T Lobovkina, RN Zare, SS Gambhir - Nanomedicine, 2011 - Taylor & Francis
Nanoparticles are an essential component in the emerging field of nanomedical imaging
and therapy. When deployed in vivo, these materials are typically protected from the immune …

Toxicity of nanomaterials

S Sharifi, S Behzadi, S Laurent, ML Forrest… - Chemical Society …, 2012 - pubs.rsc.org
Nanoscience has matured significantly during the last decade as it has transitioned from
bench top science to applied technology. Presently, nanomaterials are used in a wide …