The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Atherosclerosis is a progressive inflammatory disorder of the arterial vessel wall
characterized by substantial infiltration of macrophages, which exert both favourable and …

An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

During atherosclerosis, the gradual accumulation of lipids into the subendothelial space of
damaged arteries results in several lipid modification processes followed by macrophage …

The engulfment of apoptotic cells by phagocytes, a process referred to as efferocytosis, is
essential for maintenance of normal tissue homeostasis and a prerequisite for the resolution …

Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

The concept that chemokines, cytokines and pro-inflammatory mediators act in a co-
ordinated fashion to drive the initiation of the inflammatory reaction is well understood. The …

Uncontrolled inflammation is a leading cause of many clinically relevant diseases. Current
therapeutic strategies focus mainly on immunosuppression rather than on the mechanisms …

Neutrophils (also named polymorphonuclear leukocytes or PMN) are essential components
of the immune system, rapidly recruited to sites of inflammation, providing the first line of …

Atherosclerosis is a chronic inflammatory disorder characterized by the gradual build-up of
plaques within the vessel wall of middle-sized and large arteries. Over the past decades …