Microvascular alterations in Alzheimer's disease

J Steinman, HS Sun, ZP Feng - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder associated with continual decline
in cognition and ability to perform routine functions such as remembering familiar places or …

Complicated role of exercise in modulating memory: a discussion of the mechanisms involved

M Ebrahimnejad, P Azizi, V Alipour… - Neurochemical …, 2022 - Springer
Evidence has shown the beneficial effects of exercise on learning and memory. However,
many studies have reported controversial results, indicating that exercise can impair …

Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia

H Han, Y Zhao, J Du, S Wang, X Yang, W Li, J Song… - Immunity & …, 2023 - Springer
Background Exercise is postulated to be a promising non-pharmacological intervention for
the improvement of neurodegenerative disease pathology. However, the mechanism of …

Bushen-Yizhi formula exerts neuroprotective effect via inhibiting excessive mitophagy in rats with chronic cerebral hypoperfusion

Q **ao, H Liu, C Yang, Y Chen, Y Huang, X **ao… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Bushen-Yizhi formula (BSYZ), a traditional
Chinese medicine (TCM) prescription widely used in treating mental retardation and …

APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice

S Anderle, O Bonnar, J Henderson, K Shaw… - Communications …, 2025 - nature.com
Reduced cerebral blood flow occurs early in the development of Alzheimer's disease (AD),
but the factors producing this reduction are unknown. Here, we ask whether genetic and …

Animal models to study cognitive impairment of chronic kidney disease

PH Imenez Silva, M Pepin, A Figurek… - American Journal …, 2024 - journals.physiology.org
Mild cognitive impairment (MCI) is common in people with chronic kidney disease (CKD),
and its prevalence increases with progressive loss of kidney function. MCI is characterized …

Exploring the neuroprotective role of physical activity in cerebral small vessel disease

ME Anderson, EJ Wind, LS Robison - Brain Research, 2024 - Elsevier
Abstract Cerebral Small Vessel Disease (cSVD) is a common neurological finding
characterized by abnormalities of the small blood vessels in the brain. Previous research …

[HTML][HTML] Effect of swimming training on spatial memory of maternal deprived infants: Inducing stress by six hours separation per day

MH Sattarzadeh… - Journal of Ilam …, 2022 - sjimu.medilam.ac.ir
Discussion & Conclusion: The results showed that although stress did not have a negative
impact on spatial learning, it had a destructive impact on memory. On the other hand …

[PDF][PDF] 阿尔茨海默病患者居家护理方案的构建与应用

周娜 - **实用神经疾病杂志, 2022 - cn-shen**g.com
目的制订阿尔茨海默病(AD) 患者出院后的居家护理方案, 并探讨其应用效果. 方法2019-02—
2020-05 在郑州市第九人民医院就诊的AD 患者, 随机分为观察组和对照组 …

GABAergic LRP1 is a key link between obesity and memory function

AA Uner, ZS Hou, A Aydogan, KCC Rodrigues… - bioRxiv, 2022 - biorxiv.org
Objective Low-density lipoprotein receptor-related protein-1 (LRP1) regulates energy
homeostasis, blood-brain barrier integrity, and metabolic signaling in the brain. Loss of …