Harnessing the power of Raman spectroscopic imaging for ophthalmology
J Li, P Yan, Y Li, M Han, Q Zeng, J Li, Z Yu… - Frontiers in …, 2023 - frontiersin.org
Eye diseases can cause great inconvenience to people's daily life; therefore, it is necessary
to study the causes of ocular diseases and related physiological processes. Raman …
to study the causes of ocular diseases and related physiological processes. Raman …
Multiomics analysis reveals novel genetic determinants for lens differentiation, structure, and transparency
Recent advances in next-generation sequencing and data analysis have provided new
gateways for identification of novel genome-wide genetic determinants governing tissue …
gateways for identification of novel genome-wide genetic determinants governing tissue …
Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues
Recent reports have challenged the notion that the lens is immune-privileged. However,
these studies have not fully identified the molecular mechanism (s) that promote immune …
these studies have not fully identified the molecular mechanism (s) that promote immune …
A possible connection between reactive oxygen species and the unfolded protein response in lens development: From insight to foresight
L Gao, N **, Z Ye, T Ma, Y Huang, H Li… - Frontiers in Cell and …, 2022 - frontiersin.org
The lens is a relatively special and simple organ. It has become an ideal model to study the
common developmental characteristics among different organic systems. Lens development …
common developmental characteristics among different organic systems. Lens development …
Cataractogenesis and molecular pathways, with reactive free oxygen species as a common pathway
AIP Pacheco - Survey of Ophthalmology, 2024 - Elsevier
Slowing down or stop** the natural process of cataractogenesis is certainly a challenge
for those who today propose an option other than surgery. Addressing the same problem in …
for those who today propose an option other than surgery. Addressing the same problem in …
Glutathione safeguards TET‐dependent DNA demethylation and is critical for the acquisition of totipotency and pluripotency during preimplantation development
J Liu, M Chu, J Zhang, J He, Q Yang, L Tao… - The FASEB …, 2024 - Wiley Online Library
During early development, both genome‐wide epigenetic reprogramming and metabolic
remodeling are hallmark changes of normal embryogenesis. However, little is known about …
remodeling are hallmark changes of normal embryogenesis. However, little is known about …
TDDFT study on the simultaneous sensing mechanism for peroxynitrite and glutathione by a bifunctional fluorescent probe
W Si-Jia, L Peng-Yuan, Z Hang, S Lei, L Dong… - … Acta Part A: Molecular …, 2023 - Elsevier
Using time-dependent density functional theory (TDDFT) method, the response mechanism
of a reported bifunctional fluorescent probe for simultaneous recognition of peroxynitrite and …
of a reported bifunctional fluorescent probe for simultaneous recognition of peroxynitrite and …
[HTML][HTML] The development and the genetic diseases of the ciliary body
The ciliary body, located at the junction of the choroid and iris, is crucial in the development
of the embryonic eye. Notch2 signalling, Wnt signalling, transforming growth factor β (TGF-β) …
of the embryonic eye. Notch2 signalling, Wnt signalling, transforming growth factor β (TGF-β) …
Endocrine pancreas-specific Gclc gene deletion causes a severe diabetes phenotype
Reduced glutathione (GSH) is an abundant antioxidant that regulates intracellular redox
homeostasis by scavenging reactive oxygen species (ROS). Glutamate-cysteine ligase …
homeostasis by scavenging reactive oxygen species (ROS). Glutamate-cysteine ligase …
Anp32b Deficiency Suppresses Ocular Development by Repression of Pax6
YS Wei, HR Liu, Q Yang, Z Zhi, Y Yu - Ophthalmic Research, 2024 - karger.com
Introduction: This study aimed to elucidate the role and molecular mechanisms of acidic
leucine-rich nuclear phosphoprotein 32 kDa B (Anp32b) deficiency in ocular development …
leucine-rich nuclear phosphoprotein 32 kDa B (Anp32b) deficiency in ocular development …