A survey of protein databases indicates that the majority of enzymes exist in oligomeric
forms, with about half of those found in the UniProt database being homodimeric …

The Omp85 protein superfamily is found in the outer membrane (OM) of all gram-negative
bacteria and eukaryotic organelles of bacterial origin. Members of the family catalyze both …

The outer membrane structure is common in Gram-negative bacteria, mitochondria and
chloroplasts, and contains outer membrane β-barrel proteins (OMPs) that are essential …

The β-barrel assembly machine (BAM) integrates β-barrel proteins into the outer membrane
(OM) of Gram-negative bacteria. An essential BAM subunit (BamA) catalyzes integration by …

Mitochondria are double-membrane-bounded organelles that depend critically on
phospholipids supplied by the endoplasmic reticulum. These lipids must cross the outer …

Microbial-driven lignin conversion has a significant impact on the biogeochemistry of global
ecosystems and biomass utilization. During this process, secretion of extracellular …

Type V, or “autotransporter,” secretion is a term used to refer to several simple protein export
pathways that are found in a wide range of Gram-negative bacteria. Autotransporters are …

The type 5 secretion system (T5SS) is one of the more widespread secretion systems in
Gram-negative bacteria. Proteins secreted by the T5SS are functionally diverse (toxins …

OsmY is a widely conserved but poorly understood 20 kDa periplasmic protein. Using a
folding biosensor, we previously obtained evidence that OsmY has molecular chaperone …

Network coordinates of cellular processes (proteostasis, proteolysis, and endocytosis), and
molecular chaperones are the key complements in the cell machinery and processes …