Insertions and deletions: Computational methods, evolutionary dynamics, and biological applications

BD Redelings, I Holmes, G Lunter… - Molecular biology …, 2024 - academic.oup.com
Insertions and deletions constitute the second most important source of natural genomic
variation. Insertions and deletions make up to 25% of genomic variants in humans and are …

Phyloformer: Fast, accurate and versatile phylogenetic reconstruction with deep neural networks

L Nesterenko, L Blassel, P Veber, B Boussau, L Jacob - bioRxiv, 2024 - biorxiv.org
Phylogenetic inference aims at reconstructing the tree describing the evolution of a set of
sequences descending from a common ancestor. The high computational cost of state-of-the …

[HTML][HTML] ConvexML: Scalable and accurate inference of single-cell chronograms from CRISPR/Cas9 lineage tracing data

S Prillo, A Ravoor, N Yosef, YS Song - Biorxiv, 2023 - ncbi.nlm.nih.gov
CRISPR/Cas9 gene editing technology has enabled lineage tracing for thousands of cells in
vivo. However, most of the analysis of CRISPR/Cas9 lineage tracing data has so far been …

The chloroplast genome sequence and phylogenetic analysis of Rubia alata Wall and Rubia ovatifolia Z. Ying Zhang. (Rubiaceae)

JZ Shi, XY Chen, YY **g, Y Yan, G Zhang… - Molecular Biology …, 2024 - Springer
Abstract Background Rubia alata Wall (R. alata) and Rubia ovatifolia Z. Ying Zhang (R.
ovatifolia) are unique medicinal plants native to China. Sequencing their chloroplast …

[PDF][PDF] Novel Protein Evolution Models for Ancestral Sequence Reconstruction

A Ravoor - 2024 - digicoll.lib.berkeley.edu
Understanding the evolution of proteins over time is crucial to a variety of applications in
biology such as phylogenetic tree reconstruction, ancestral sequence reconstruction …

Ultrafast classical phylogenetic method beats large protein language models on variant effect prediction

S Prillo, WY Wu, YS Song - The Thirty-eighth Annual Conference on Neural … - openreview.net
Amino acid substitution rate matrices are fundamental to statistical phylogenetics and
evolutionary biology. Estimating them typically requires reconstructed trees for massive …

[인용][C] CherryML 2.0: Almost Linear Time Estimation of Phylogenetic Models

W Wu - 2024