Ancient pathogen genomics as an emerging tool for infectious disease research

MA Spyrou, KI Bos, A Herbig, J Krause - Nature Reviews Genetics, 2019 - nature.com
Over the past decade, a genomics revolution, made possible through the development of
high-throughput sequencing, has triggered considerable progress in the study of ancient …

Plague

MB Prentice, L Rahalison - The Lancet, 2007 - thelancet.com
Bubonic plague is an often fulminant systemic zoonosis, caused by Yersinia pestis.
Conventional microbiology, bacterial population genetics, and genome sequence data, all …

[HTML][HTML] Emergence and spread of basal lineages of Yersinia pestis during the Neolithic decline

N Rascovan, KG Sjögren, K Kristiansen, R Nielsen… - Cell, 2019 - cell.com
Summary Between 5,000 and 6,000 years ago, many Neolithic societies declined
throughout western Eurasia due to a combination of factors that are still largely debated …

A draft genome of Yersinia pestis from victims of the Black Death

KI Bos, VJ Schuenemann, GB Golding, HA Burbano… - Nature, 2011 - nature.com
Technological advances in DNA recovery and sequencing have drastically expanded the
scope of genetic analyses of ancient specimens to the extent that full genomic investigations …

Analysis of 3800-year-old Yersinia pestis genomes suggests Bronze Age origin for bubonic plague

MA Spyrou, RI Tukhbatova, CC Wang… - Nature …, 2018 - nature.com
The origin of Yersinia pestis and the early stages of its evolution are fundamental subjects of
investigation given its high virulence and mortality that resulted from past pandemics …

Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis

Y Cui, C Yu, Y Yan, D Li, Y Li… - Proceedings of the …, 2013 - National Acad Sciences
The genetic diversity of Yersinia pestis, the etiologic agent of plague, is extremely limited
because of its recent origin coupled with a slow clock rate. Here we identified 2,326 SNPs …

Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity

G Morelli, Y Song, CJ Mazzoni, M Ep**er… - Nature …, 2010 - nature.com
Plague is a pandemic human invasive disease caused by the bacterial agent Yersinia
pestis. We here report a comparison of 17 whole genomes of Y. pestis isolates from global …

Autoinducer 2 Controls Biofilm Formation in Escherichia coli through a Novel Motility Quorum-Sensing Regulator (MqsR, B3022)

AF González Barrios, R Zuo, Y Hashimoto… - Journal of …, 2006 - Am Soc Microbiol
The cross-species bacterial communication signal autoinducer 2 (AI-2), produced by the
purified enzymes Pfs (nucleosidase) and LuxS (terminal synthase) from S …

Microevolution and history of the plague bacillus, Yersinia pestis

M Achtman, G Morelli, P Zhu, T Wirth… - Proceedings of the …, 2004 - National Acad Sciences
The association of historical plague pandemics with Yersinia pestis remains controversial,
partly because the evolutionary history of this largely monomorphic bacterium was unknown …

Genetic Structure and Distribution of the Colibactin Genomic Island among Members of the Family Enterobacteriaceae

J Putze, C Hennequin, JP Nougayrede… - Infection and …, 2009 - Am Soc Microbiol
ABSTRACT A genomic island encoding the biosynthesis and secretion pathway of putative
hybrid nonribosomal peptide-polyketide colibactin has been recently described in …