Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at
an unprecedented temporal precision for neurological disorders. This has the potential to …

Neurotechnologies combine engineering methods and neuroscientific knowledge to design
devices that interface the brain with the outside world. Since the early 2000s, inspiring and …

Deep brain stimulation (DBS) is a widely used therapy for Parkinson's disease (PD) but
lacks dynamic responsiveness to changing clinical and neural states. Feedback control …

People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor
deficits that are resistant to currently available therapies. To alleviate these deficits, we …

Neural recordings using invasive devices in humans can elucidate the circuits underlying
brain disorders, but have so far been limited to short recordings from externalized brain …

Beta oscillations (∼ 13 to 30 Hz) have been observed during many perceptual, cognitive,
and motor processes in a plethora of brain recording studies. Although the function of beta …

Objective. Individuals with neurological disease or injury such as amyotrophic lateral
sclerosis, spinal cord injury or stroke may become tetraplegic, unable to speak or even …

Background Closed loop deep brain stimulation (clDBS) in Parkinson's disease (PD) using
subthalamic (STN) neural feedback has been shown to be efficacious only in the acute post …

Detection of neural signatures related to pathological behavioral states could enable
adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for …

Advances in technologies that can record and stimulate deep brain activity in humans have
led to impactful discoveries within the field of neuroscience and contributed to the …