The pathology of asthma: what is obstructing our view?
H Aegerter, BN Lambrecht - Annual Review of Pathology …, 2023 - annualreviews.org
Despite the advent of sophisticated and efficient new biologics to treat inflammation in
asthma, the disease persists. Even following treatment, many patients still experience the …
asthma, the disease persists. Even following treatment, many patients still experience the …
Neutrophil extracellular traps in cancer
L Cristinziano, L Modestino, A Antonelli… - Seminars in cancer …, 2022 - Elsevier
Beyond their well-known functions in the acute phases of the immune response, neutrophils
play important roles in the various phases of tumor initiation and progression, through the …
play important roles in the various phases of tumor initiation and progression, through the …
Eosinophils from A to Z
L Gigon, T Fettrelet, S Yousefi, D Simon, HU Simon - Allergy, 2023 - Wiley Online Library
Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …
The roles of IL-5 and anti-IL-5 treatment in eosinophilic diseases: Asthma, eosinophilic granulomatosis with polyangiitis, and eosinophilic chronic rhinosinusitis
H Nagase, S Ueki, S Fujieda - Allergology International, 2020 - jstage.jst.go.jp
abstract IL-5 is the most potent activator of eosinophils and is produced by Th2 cells and
ILC2s. A role for IL-5 in eosinophil extracellular trap cell death, ie, a proinflammatory cell …
ILC2s. A role for IL-5 in eosinophil extracellular trap cell death, ie, a proinflammatory cell …
Revised clinical practice guidelines for diagnosing, classifying, and treating allergic bronchopulmonary aspergillosis/mycoses: a Delphi statement from the ISHAM …
Background The ISHAM working group proposed recommendations for managing allergic
bronchopulmonary aspergillosis (ABPA) nearly a decade ago. There is a need to update …
bronchopulmonary aspergillosis (ABPA) nearly a decade ago. There is a need to update …
Neutrophil extracellular traps, angiogenesis and cancer
Human neutrophils, the most abundant circulating leukocytes, are fundamental components
of the host response against different pathogens. Until a few years ago, neutrophils received …
of the host response against different pathogens. Until a few years ago, neutrophils received …
Charcot-Leyden crystal formation is closely associated with eosinophil extracellular trap cell death
Protein crystallization in human tissue rarely occurs. Charcot-Leyden crystals (CLCs) were
described in various eosinophilic diseases> 150 years ago, but our understanding of CLC …
described in various eosinophilic diseases> 150 years ago, but our understanding of CLC …
Adult‐onset eosinophilic airway diseases
K Asano, S Ueki, M Tamari, Y Imoto, S Fujieda… - Allergy, 2020 - Wiley Online Library
Eosinophilic airway inflammation is one of the cardinal features of allergic airway diseases
such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated …
such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated …
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease
Eosinophils are bone marrow-derived granulocytes that are traditionally associated with
type 2 immune responses, such as those that occur during parasite infections and allergy …
type 2 immune responses, such as those that occur during parasite infections and allergy …
The cellular functions of eosinophils: Collegium Internationale Allergologicum (CIA) update 2020
Eosinophils and their secretory mediators play an important role in the pathogenesis of
infectious and inflammatory disorders. Although eosinophils are largely evolutionally …
infectious and inflammatory disorders. Although eosinophils are largely evolutionally …