Impact of patient and public involvement on enrolment and retention in clinical trials: systematic review and meta-analysis
Objective To investigate the impact of patient and public involvement (PPI) on rates of
enrolment and retention in clinical trials and explore how this varies with the context and …
enrolment and retention in clinical trials and explore how this varies with the context and …
COSCA (Core Outcome Set for Cardiac Arrest) in adults: an advisory statement from the International Liaison Committee on Resuscitation
Cardiac arrest effectiveness trials have traditionally reported outcomes that focus on
survival. A lack of consistency in outcome reporting between trials limits the opportunities to …
survival. A lack of consistency in outcome reporting between trials limits the opportunities to …
No surgical innovation without evaluation: evolution and further development of the IDEAL framework and recommendations
A Hirst, Y Philippou, J Blazeby, B Campbell… - Annals of …, 2019 - journals.lww.com
Objective: To update, clarify, and extend IDEAL concepts and recommendations.
Background: New surgical procedures, devices, and other complex interventions need …
Background: New surgical procedures, devices, and other complex interventions need …
Develo** a roadmap to improve trial delivery for under-served groups: results from a UK multi-stakeholder process
Background Participants in clinical research studies often do not reflect the populations for
which healthcare interventions are needed or will be used. Enhancing representation of …
which healthcare interventions are needed or will be used. Enhancing representation of …
Blockchain protocols in clinical trials: Transparency and traceability of consent
M Benchoufi, R Porcher, P Ravaud - F1000Research, 2018 - pmc.ncbi.nlm.nih.gov
Clinical trial consent for protocols and their revisions should be transparent for patients and
traceable for stakeholders. Our goal is to implement a process allowing for collection of …
traceable for stakeholders. Our goal is to implement a process allowing for collection of …
Trial forge guidance 1: what is a study within a trial (SWAT)?
Randomised trials are a central component of all evidence-informed health care systems
and the evidence coming from them helps to support health care users, health professionals …
and the evidence coming from them helps to support health care users, health professionals …
A patient and public involvement (PPI) toolkit for meaningful and flexible involvement in clinical trials–a work in progress
HJ Bagley, H Short, NL Harman, HR Hickey… - Research involvement …, 2016 - Springer
Plain Language Summary Funders of research are increasingly requiring researchers to
involve patients and the public in their research. Patient and public involvement (PPI) in …
involve patients and the public in their research. Patient and public involvement (PPI) in …
A systematic review of discontinued trials suggested that most reasons for recruitment failure were preventable
Objective To collect and classify reported reasons for recruitment failure in discontinued
randomized controlled trials (RCTs) and to assess reporting quality. Methods We …
randomized controlled trials (RCTs) and to assess reporting quality. Methods We …
Generating comparative evidence on new drugs and devices before approval
Fewer than half of new drugs have data on their comparative benefits and harms against
existing treatment options at the time of regulatory approval in Europe and the USA. Even …
existing treatment options at the time of regulatory approval in Europe and the USA. Even …
[HTML][HTML] The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation
Objective To evaluate the impact of the QuinteT Recruitment Intervention (QRI) on
recruitment in challenging randomized controlled trials (RCTs) that have applied the …
recruitment in challenging randomized controlled trials (RCTs) that have applied the …