Nanodiscs in membrane biochemistry and biophysics

IG Denisov, SG Sligar - Chemical reviews, 2017 - ACS Publications
Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Biosensing with plasmonic nanosensors

JN Anker, WP Hall, O Lyandres, NC Shah, J Zhao… - Nature materials, 2008 - nature.com
Recent developments have greatly improved the sensitivity of optical sensors based on
metal nanoparticle arrays and single nanoparticles. We introduce the localized surface …

Nanodiscs: A toolkit for membrane protein science

SG Sligar, IG Denisov - Protein Science, 2021 - Wiley Online Library
Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

Structure and chemistry of cytochrome P450

IG Denisov, TM Makris, SG Sligar… - Chemical reviews, 2005 - ACS Publications
The title to a seminar presentation by IC Gunsalus in 1973 was “Oxygen: An essential toxin”,
referring to the complex role that atmospheric dioxygen has in biology. The relatively simple …

P450 Enzymes: Their Structure, Reactivity, and Selectivity Modeled by QM/MM Calculations

S Shaik, S Cohen, Y Wang, H Chen, D Kumar… - Chemical …, 2010 - ACS Publications
The introduction of oxygen into biochemical processes has brought about an evolutionary
leap in the history of life, whereby many organisms have evolved to use oxygen as part of …

Theoretical perspective on the structure and mechanism of cytochrome P450 enzymes

S Shaik, D Kumar, SP de Visser, A Altun… - Chemical …, 2005 - ACS Publications
Cytochrome P450 is one of the most versatile enzymes in nature. 1 It uses dioxygen and two
reducing equivalents to catalyze a great variety of stereospecific and regioselective oxygen …

[KNJIGA][B] Modern oxidation methods

JE Bäckvall - 2011 - books.google.com
While rust is an unwanted oxidation reaction, there are also many other useful oxidation
reactions that are extremely important and number among the most commonly used …

Structure and function of the cytochrome P450 peroxygenase enzymes

AW Munro, KJ McLean, JL Grant… - Biochemical Society …, 2018 - portlandpress.com
The cytochromes P450 (P450s or CYPs) constitute a large heme enzyme superfamily,
members of which catalyze the oxidative transformation of a wide range of organic …

The many roles of cytochrome b5

JB Schenkman, I Jansson - Pharmacology & therapeutics, 2003 - Elsevier
Four distinct suggestions have been made to explain the mechanism of the cytochrome b5-
imposed positive modifier action of the cytochrome P450 monooxygenase reaction. The first …

[KNJIGA][B] Isotope effects in chemistry and biology

A Kohen, HH Limbach - 2005 - taylorfrancis.com
The field of isotope effects has expanded exponentially in the last decade, and researchers
are finding isotopes increasingly useful in their studies. Bringing literature on the subject up …