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Application of artificial intelligence technology in oncology: Towards the establishment of precision medicine
Simple Summary Artificial intelligence (AI) technology has been advancing rapidly in recent
years and is being implemented in society. The medical field is no exception, and the clinical …
years and is being implemented in society. The medical field is no exception, and the clinical …
N6-Methyladenosine RNA modification in the tumor immune microenvironment: novel implications for immunotherapy
L Guo, H Yang, C Zhou, Y Shi, L Huang… - Frontiers in …, 2021 - frontiersin.org
N6-methyladenosine (m6A) methylation is one of the most common modifications of RNA in
eukaryotic cells, and is mainly regulated by m6A methyltransferases (writers), m6A …
eukaryotic cells, and is mainly regulated by m6A methyltransferases (writers), m6A …
Integrated analysis of whole genome and epigenome data using machine learning technology: toward the establishment of precision oncology
With the completion of the International Human Genome Project, we have entered what is
known as the post-genome era, and efforts to apply genomic information to medicine have …
known as the post-genome era, and efforts to apply genomic information to medicine have …
Regulation of m6A methylation as a new therapeutic option against COVID-19
The rapid spread of SARS-CoV-2 and the resulting pandemic has led to a spasmodic search
for approaches able to limit the diffusion of the disease. The epigenetic machinery has …
for approaches able to limit the diffusion of the disease. The epigenetic machinery has …
A Light‐Controllable Chemical Modulation of m6A RNA Methylation
L Lan, YJ Sun, XY **, LJ **e, L Liu… - Angewandte …, 2021 - Wiley Online Library
Bioactive small molecules with photo‐removable protecting groups have provided spatial
and temporal control of corresponding biological effects. We present the design, synthesis …
and temporal control of corresponding biological effects. We present the design, synthesis …
Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules
A Bolatkan, K Asada, S Kaneko… - International …, 2021 - spandidos-publications.com
RNA modifications have attracted increasing interest in recent years because they have
been frequently implicated in various human diseases, including cancer, highlighting the …
been frequently implicated in various human diseases, including cancer, highlighting the …
[HTML][HTML] On the specificity of the recognition of m6A-RNA by YTH reader domains
Most processes of life are the result of polyvalent interactions between macromolecules,
often of heterogeneous types and sizes. Frequently, the times associated with these …
often of heterogeneous types and sizes. Frequently, the times associated with these …
RNA m6A methylation regulators in liver cancer
Q Xu, N Ren, L Ren, Y Yang, J Pan, H Shang - Cancer Cell International, 2024 - Springer
Liver cancer is one of the most common cancers in the world and a primary cause of cancer-
related death. In recent years, despite the great development of diagnostic methods and …
related death. In recent years, despite the great development of diagnostic methods and …
[HTML][HTML] METTL3 promotes the growth and metastasis of pancreatic cancer by regulating the m6A modification and stability of E2F5
Y Tang, G Gao, W **a, J Wang - Cellular signalling, 2022 - Elsevier
Background Pancreatic cancer belongs to lethal cancer with limited efficient treatment
currently, and its main cause of death is rapid tumor growth and early metastasis. N6 …
currently, and its main cause of death is rapid tumor growth and early metastasis. N6 …
Pseudorabies virus exploits N6-methyladenosine modification to promote viral replication
PL Yu, R Wu, SJ Cao, YP Wen, XB Huang… - Frontiers in …, 2023 - frontiersin.org
Introduction Pseudorabies virus (PRV) is the pathogenic virus of porcine pseudorabies (PR),
belonging to the Herpesviridae family. PRV has a wide range of hosts and in recent years …
belonging to the Herpesviridae family. PRV has a wide range of hosts and in recent years …