[HTML][HTML] Genetics of attention deficit hyperactivity disorder
Decades of research show that genes play an vital role in the etiology of attention deficit
hyperactivity disorder (ADHD) and its comorbidity with other disorders. Family, twin, and …
hyperactivity disorder (ADHD) and its comorbidity with other disorders. Family, twin, and …
[HTML][HTML] Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan
Attention-deficit/hyperactivity disorder (ADHD) is highly heritable and the most common
neurodevelopmental disorder in childhood. In recent decades, it has been appreciated that …
neurodevelopmental disorder in childhood. In recent decades, it has been appreciated that …
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …
mood and anhedonia. Depression has a heritable component that has remained difficult to …
Genetics of glutamate and its receptors in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …
deficits in social interaction skills, impaired communication, and repetitive and restricted …
[HTML][HTML] Integrative analysis of 111 reference human epigenomes
The reference human genome sequence set the stage for studies of genetic variation and its
association with human disease, but epigenomic studies lack a similar reference. To …
association with human disease, but epigenomic studies lack a similar reference. To …
HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease
More than 90% of common variants associated with complex traits do not affect proteins
directly, but instead the circuits that control gene expression. This has increased the urgency …
directly, but instead the circuits that control gene expression. This has increased the urgency …
Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors
In the develo** central nervous system (CNS), the control of synapse number and function
is critical to the formation of neural circuits. We previously demonstrated that astrocyte …
is critical to the formation of neural circuits. We previously demonstrated that astrocyte …
Common genetic variation influencing human white matter microstructure
INTRODUCTION White matter in the human brain serves a critical role in organizing
distributed neural networks. Diffusion magnetic resonance imaging (dMRI) has enabled the …
distributed neural networks. Diffusion magnetic resonance imaging (dMRI) has enabled the …
The genetics of attention deficit/hyperactivity disorder in adults, a review
The adult form of attention deficit/hyperactivity disorder (aADHD) has a prevalence of up to
5% and is the most severe long-term outcome of this common neurodevelopmental disorder …
5% and is the most severe long-term outcome of this common neurodevelopmental disorder …