With the acceleration of population aging, nervous system diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), Huntington's disease (HD), anxiety, depression …

The balance between oxidation and antioxidant is crucial for maintaining homeostasis. Once
disrupted, it can lead to various pathological outcomes and diseases, such as depression …

Background The inflammation and oxidative stress (OS) have been considered crucial
components of the pathogenesis of depression. Edaravone (EDA), a free radical scavenger …

Amyotrophic lateral sclerosis (ALS), a devastating motor neuron disease involving complex
genetic and environmental factors, is associated with neuroinflammation. Preclinical and …

Inflammation and depression are closely inter-related; inflammation induces symptoms of
depression and, conversely, depressed mood and stress favor an inflammatory phenotype …

Chronic stress exposure can produce deleterious effects on the hippocampus (HC) which
eventually leads to cognitive impairment and depression. Endoplasmic reticulum (ER) stress …

Cisplatin is a chemotherapeutic agent used in the treatment of malignant tumors. A major
clinical limitation of cisplatin is its potential toxic effects, including neurotoxicity. Edaravone …

Depression is one of the main factors affecting our daily performance. Among many putative
compounds with effect on behavioral and pathophysiological alterations in depression …

Autism spectrum disorder (ASD) is neurodevelopmental disorder with a high incidence rate,
characterized by social deficits and repetitive behaviors. There is currently no effective …

The aim of the present study was to investigate the protective effects of curcumin alone and
in combination with piperine against lipopolysaccharide (LPS)-induced neurobehavioral …