Virulence factors in coagulase-negative staphylococci

A França, V Gaio, N Lopes, LDR Melo - Pathogens, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-
associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S …

The age of phage: friend or foe in the new dawn of therapeutic and biocontrol applications?

AY Hassan, JT Lin, N Ricker, H Anany - Pharmaceuticals, 2021 - mdpi.com
Extended overuse and misuse of antibiotics and other antibacterial agents has resulted in
an antimicrobial resistance crisis. Bacteriophages, viruses that infect bacteria, have …

Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy

M Liu, A Hernandez-Morales, J Clark, T Le… - Nature …, 2022 - nature.com
Abstract In 2016, a 68-year-old patient with a disseminated multidrug-resistant Acinetobacter
baumannii infection was successfully treated using lytic bacteriophages. Here we report the …

Distribution of antimicrobial resistance and virulence genes within the prophage-associated regions in nosocomial pathogens

K Kondo, M Kawano, M Sugai - Msphere, 2021 - Am Soc Microbiol
Prophages are often involved in host survival strategies and contribute toward increasing
the genetic diversity of the host genome. Prophages also drive horizontal propagation of …

Phages carry interbacterial weapons encoded by biosynthetic gene clusters

A Dragoš, AJC Andersen, CN Lozano-Andrade… - Current Biology, 2021 - cell.com
Bacteria produce diverse specialized metabolites that mediate ecological interactions and
serve as a rich source of industrially relevant natural products. Biosynthetic pathways for …

A Biological Inventory of Prophages in A. baumannii Genomes Reveal Distinct Distributions in Classes, Length, and Genomic Positions

B Loh, J Chen, P Manohar, Y Yu, X Hua… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is of major clinical importance as the bacterial pathogen often
causes hospital acquired infections, further complicated by the high prevalence of antibiotic …

The interaction of phages and bacteria: the co-evolutionary arms race

F Safari, M Sharifi, S Farajnia, B Akbari… - Critical reviews in …, 2020 - Taylor & Francis
Since the dawn of life, bacteria and phages are locked in a constant battle and both are
perpetually changing their tactics to overcome each other. Bacteria use various strategies to …

Pan-Genome Plasticity and Virulence Factors: A Natural Treasure Trove for Acinetobacter baumannii

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2024 - mdpi.com
Acinetobacter baumannii is a Gram-negative pathogen responsible for a variety of
community-and hospital-acquired infections. It is recognized as a life-threatening pathogen …

Acinetobacter baumannii phages: past, present and future

Q Tu, M Pu, Y Li, Y Wang, M Li, L Song, M Li, X An… - Viruses, 2023 - mdpi.com
Acinetobacter baumannii (A. baumannii) is one of the most common clinical pathogens and
a typical multi-drug resistant (MDR) bacterium. With the increase of drug-resistant A …

Mining of thousands of prokaryotic genomes reveals high abundance of prophages with a strictly narrow host range

G López-Leal, LC Camelo-Valera… - Msystems, 2022 - Am Soc Microbiol
Phages and prophages are one of the principal modulators of microbial populations.
However, much of their diversity is still poorly understood. Here, we extracted 33,624 …