[HTML][HTML] Cellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components

R Augustine, A Hasan, R Primavera, RJ Wilson… - Materials Today …, 2020 - Elsevier
The utilization of nanomaterials in the biological and medical field is quickly progressing,
particularly in areas where traditional diagnostics and treatment approaches have limited …

Stiffness sensing by cells

PA Janmey, DA Fletcher… - Physiological …, 2020 - journals.physiology.org
Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

Form follows function: nanoparticle shape and its implications for nanomedicine

C Kinnear, TL Moore, L Rodriguez-Lorenzo… - Chemical …, 2017 - ACS Publications
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …

Physical principles of nanoparticle cellular endocytosis

S Zhang, H Gao, G Bao - ACS nano, 2015 - ACS Publications
This review article focuses on the physiochemical mechanisms underlying nanoparticle
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …

Effect of biophysical properties of tumor extracellular matrix on intratumoral fate of nanoparticles: Implications on the design of nanomedicine

Y Tian, T Cheng, F Sun, Y Zhou, C Yuan, Z Guo… - Advances in Colloid and …, 2024 - Elsevier
Nanomedicine has a profound impact on various research domains including drug delivery,
diagnostics, theranostics, and regenerative medicine. Nevertheless, the clinical translation …

Anisotropic nanomaterials for shape-dependent physicochemical and biomedical applications

L Yang, Z Zhou, J Song, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
This review contributes towards a systematic understanding of the mechanism of shape-
dependent effects on nanoparticles (NPs) for elaborating and predicting their properties and …

[HTML][HTML] Biophysical regulation of cell behavior—cross talk between substrate stiffness and nanotopography

Y Yang, K Wang, X Gu, KW Leong - Engineering, 2017 - Elsevier
The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

Multifunctional nanoplatforms for subcellular delivery of drugs in cancer therapy

X Guo, X Wei, Z Chen, X Zhang, G Yang… - Progress in Materials …, 2020 - Elsevier
To achieve highly effective treatment to diseases, successful delivery of drugs with a carrier
into the specific organelles (nucleus, mitochondria, lysosomes, etc.) is of great importance …

Stem cell mechanobiology and the role of biomaterials in governing mechanotransduction and matrix production for tissue regeneration

SM Naqvi, LM McNamara - Frontiers in bioengineering and …, 2020 - frontiersin.org
Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

Beyond the promise: Exploring the complex interactions of nanoparticles within biological systems

Y Ji, Y Wang, X Wang, C Lv, Q Zhou, G Jiang… - Journal of hazardous …, 2024 - Elsevier
The exploration of nanoparticle applications is filled with promise, but their impact on the
environment and human health raises growing concerns. These tiny environmental particles …