There has been an exponential growth in the performance and output of sequencing
technologies (omics data) with full genome sequencing now producing gigabases of reads …

Recently, there has been growing interest in genome sequencing, driven by advances in
sequencing technology, in terms of both efficiency and affordability. These developments …

The ever increasing growth of the production of high-throughput sequencing data poses a
serious challenge to the storage, processing and transmission of these data. As frequently …

Given the popularity and elegance of k-mer-based tools, finding a space-efficient way to
represent a set of k-mers is important for improving the scalability of bioinformatics analyses …

Background The increasing production of genomic data has led to an intensified need for
models that can cope efficiently with the lossless compression of DNA sequences. Important …

DNA sequence databases use compression such as gzip to reduce the required storage
space and network transmission time. We describe Nucleotide Archival Format (NAF)—a …

The number of genomic sequences is growing substantially. Besides discarding part of the
data, the only efficient possibility for co** with this trend is data compression. We present …

Background Nearly all molecular sequence databases currently use gzip for data
compression. Ongoing rapid accumulation of stored data calls for a more efficient …

The amount of data produced by modern sequencing instruments that needs to be stored is
huge. Therefore it is not surprising that a lot of work has been done in the field of specialized …

Abstract Motivation New Generation Sequencing (NGS) technologies for genome
sequencing produce large amounts of short genomic reads per experiment, which are highly …