Saffron (Crocus sativus L.), the king of spices: An overview
L Cardone, D Castronuovo, M Perniola, N Cicco… - Scientia …, 2020 - Elsevier
Saffron is obtained from the dried red stigmas of Crocus sativus L., an autumnal herbaceous
flowering plant belonging to the Iridaceae family. It is largely cultivated in Iran, India …
flowering plant belonging to the Iridaceae family. It is largely cultivated in Iran, India …
The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing
X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …
complications of diabetes, which seriously affects patients' quality of life and even causes …
Polygonatum sibiricum polysaccharide prevents depression-like behaviors by reducing oxidative stress, inflammation, and cellular and synaptic damage
F Shen, Z Song, P **e, L Li, B Wang, D Peng… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance According to traditional Chinese medicine (TCM) theory
(Yi Xue Zheng Zhuan), the main factors associated with the pathogenesis of depression are …
(Yi Xue Zheng Zhuan), the main factors associated with the pathogenesis of depression are …
Crocin inhibits angiogenesis and metastasis in colon cancer via TNF-α/NF-kB/VEGF pathways
Angiogenesis and metastasis play pivotal roles in the progression of cancer. We recently
discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the …
discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the …
Multi-spectroscopic investigation, molecular docking and molecular dynamic simulation of competitive interactions between flavonoids (quercetin and rutin) and …
The main mechanism for drug-drug interaction is displacement reaction of ligands from their
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …
Saffron and its major ingredients' effect on colon cancer cells with mismatch repair deficiency and microsatellite instability
Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. One
of its subtypes is associated with defective mismatch repair (dMMR) genes. Saffron has …
of its subtypes is associated with defective mismatch repair (dMMR) genes. Saffron has …
Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …
products and their derived biomolecules are potential resources to mine for novel anti …
ROS and iron homeostasis dependent ferroptosis play a vital role in 5-Fluorouracil induced cardiotoxicity in vitro and in vivo
D Li, C Song, J Zhang, X Zhao - Toxicology, 2022 - Elsevier
Fluorouracil (5-FU) was a key chemotherapeutic agent in the treatment of different solid
tumors. However, cardiotoxicity was included among the therapeutic strategies of 5-FU. The …
tumors. However, cardiotoxicity was included among the therapeutic strategies of 5-FU. The …
[HTML][HTML] Therapeutic potential of camel milk exosomes against HepaRG cells with potent apoptotic, anti-inflammatory, and anti-angiogenesis effects for colostrum …
AM El-Kattawy, O Algezawy, MY Alfaifi… - Biomedicine & …, 2021 - Elsevier
This study aimed to evaluate and compare the therapeutic effect of camel milk exosomes
derived from colostrum, early, mid, and late lactation periods on liver cancer HepaRG cells …
derived from colostrum, early, mid, and late lactation periods on liver cancer HepaRG cells …
Medicinal plants and their impact on the gut microbiome in mental health: A systematic review
Background: Various neurocognitive and mental health-related conditions have been
associated with the gut microbiome, implicating a microbiome–gut–brain axis (MGBA). The …
associated with the gut microbiome, implicating a microbiome–gut–brain axis (MGBA). The …