Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …

Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

The intricate and delicate anatomy of the brain poses significant challenges for the treatment
of cerebrovascular and neurodegenerative diseases. Thus, precise local drug delivery in …

The ability to physically manipulate specific cells is critical for the fields of biomedicine,
synthetic biology, and living materials. Ultrasound has the ability to manipulate cells with …

Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

Beyond the emerging field of oncological ultrasound molecular imaging, the recent
significant advancements in ultrasound and contrast agent technology have paved the way …

Ultrasound is extensively used in medical imaging, being safe and inexpensive and
operating in real time. Its scope of applications has been widely broadened by the use of …

Drug delivery for tumor theranostics involves the extensive use of the enhanced permeability
and retention (EPR) effect. Previously, various types of nanomedicines have been …

Drug delivery to the brain is crucial in the treatment for central nervous system disorders.
While significant progress has been made in recent years, there are still major challenges in …

In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …