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Ribosome biogenesis factors—from names to functions
The assembly of ribosomal subunits is a highly orchestrated process that involves a huge
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …
The mechanism of eukaryotic translation initiation and principles of its regulation
Protein synthesis is principally regulated at the initiation stage (rather than during elongation
or termination), allowing rapid, reversible and spatial control of gene expression. Progress …
or termination), allowing rapid, reversible and spatial control of gene expression. Progress …
Structured elements drive extensive circular RNA translation
The human genome encodes tens of thousands circular RNAs (circRNAs) with mostly
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
The structure of the eukaryotic ribosome at 3.0 Å resolution
Ribosomes translate genetic information encoded by messenger RNA into proteins. Many
aspects of translation and its regulation are specific to eukaryotes, whose ribosomes are …
aspects of translation and its regulation are specific to eukaryotes, whose ribosomes are …
Comparative protein structure modeling using MODELLER
Comparative protein structure modeling predicts the three‐dimensional structure of a given
protein sequence (target) based primarily on its alignment to one or more proteins of known …
protein sequence (target) based primarily on its alignment to one or more proteins of known …
Comparative protein structure modeling using Modeller
Functional characterization of a protein sequence is one of the most frequent problems in
biology. This task is usually facilitated by accurate three‐dimensional (3‐D) structure of the …
biology. This task is usually facilitated by accurate three‐dimensional (3‐D) structure of the …
One core, two shells: bacterial and eukaryotic ribosomes
Ribosomes are universally conserved enzymes that carry out protein biosynthesis. Bacterial
and eukaryotic ribosomes, which share an evolutionarily conserved core, are thought to …
and eukaryotic ribosomes, which share an evolutionarily conserved core, are thought to …
Principles of selective ion transport in channels and pumps
The transport of ions across the membranes of cells and organelles is a prerequisite for
many of life's processes. Transport often involves very precise selectivity for specific ions …
many of life's processes. Transport often involves very precise selectivity for specific ions …
The structure and function of the eukaryotic ribosome
Structures of the bacterial ribosome have provided a framework for understanding universal
mechanisms of protein synthesis. However, the eukaryotic ribosome is much larger than it is …
mechanisms of protein synthesis. However, the eukaryotic ribosome is much larger than it is …
[ספר][B] Three-dimensional electron microscopy of macromolecular assemblies: visualization of biological molecules in their native state
J Frank - 2006 - books.google.com
Cryoelectron microscopy of biological molecules is among the hottest growth areas in
biophysics and structural biology at present, and Frank is arguably the most distinguished …
biophysics and structural biology at present, and Frank is arguably the most distinguished …