Tau and amyloid beta (Aβ) are the prime suspects for driving pathology in Alzheimer's
disease (AD) and, as such, have become the focus of therapeutic development. Recent …

The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to
play key roles in Alzheimer's disease pathogenesis and are considered the main …

Most metastasizing tumor cells reach distant sites by entering the circulatory system. Within
the bloodstream, they are exposed to severe stress due to loss of adhesion to extracellular …

The extracellular vesicle (EV) surface proteome (surfaceome) acts as a fundamental
signalling gateway by bridging intra‐and extracellular signalling networks, dictates EVs' …

Amyloid precursor protein (APP) is a type 1 transmembrane glycoprotein, and its homologs
amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are …

Alterations in membrane proteins (MPs) and their regulated pathways have been
established as cancer hallmarks and extensively targeted in clinical applications. However …

ABSTRACT A bispecific antibody (bsAb) is able to bind two different targets or two distinct
epitopes on the same target. Broadly speaking, bsAbs can include any single molecule …

Background Copper was reported to be involved in the onset and progression of cancer.
Proteins in charge of copper uptake and distribution, as well as cuproenzymes, are altered …

Bovine mycoplasmosis is an important infectious disease of cattle caused by Mycoplasma
bovis (M. bovis) which poses a serious threat to the breeding industry. Adhesin is involved in …

The cancer secretome comprises factors secreted by tumors, including cytokines, growth
factors, proteins from the extracellular matrix (ECM), proteases and protease inhibitors …