Colonocyte metabolism shapes the gut microbiota

Y Litvak, MX Byndloss, AJ Bäumler - Science, 2018 - science.org
BACKGROUND An imbalance in the colonic microbiota might underlie many human
diseases, but the mechanisms that balance our microbial self during homeostasis have long …

Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART

S Zicari, L Sessa, N Cotugno, A Ruggiero, E Morrocchi… - Viruses, 2019 - mdpi.com
Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …

The immune response to Prevotella bacteria in chronic inflammatory disease

JM Larsen - Immunology, 2017 - Wiley Online Library
The microbiota plays a central role in human health and disease by sha** immune
development, immune responses and metabolism, and by protecting from invading …

Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non-responders

X Yang, B Su, X Zhang, Y Liu, H Wu… - Journal of leukocyte …, 2020 - academic.oup.com
The morbidity and mortality of HIV type-1 (HIV-1)-related diseases were dramatically
diminished by the grounds of the introduction of potent antiretroviral therapy, which induces …

HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Altered virome and bacterial microbiome in human immunodeficiency virus-associated acquired immunodeficiency syndrome

CL Monaco, DB Gootenberg, G Zhao, SA Handley… - Cell host & …, 2016 - cell.com
Human immunodeficiency virus (HIV) infection is associated with increased intestinal
translocation of microbial products and enteropathy as well as alterations in gut bacterial …

Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging

S Singh, LB Giron, MW Shaikh, S Shankaran… - Microbiome, 2024 - Springer
Background People living with HIV (PLWH), even when viral replication is controlled through
antiretroviral therapy (ART), experience persistent inflammation. This inflammation is partly …

Gut microbiota linked to sexual preference and HIV infection

M Noguera-Julian, M Rocafort, Y Guillén, J Rivera… - …, 2016 - thelancet.com
The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies
provided contradictory associations between microbial richness and HIV serostatus and …

Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection

DM Dinh, GE Volpe, C Duffalo… - The Journal of …, 2015 - academic.oup.com
Background. Despite effective antiretroviral therapy (ART), patients with chronic human
immunodeficiency virus (HIV) infection have increased microbial translocation and systemic …

Gut microbiota diversity predicts immune status in HIV-1 infection

P Nowak, M Troseid, E Avershina, B Barqasho… - Aids, 2015 - journals.lww.com
Objective: HIV-1 infection is characterized by altered intestinal barrier, gut microbiota
dysbiosis, and systemic inflammation. We hypothesized that changes of the gut microbiota …