Revisiting IL-2: Biology and therapeutic prospects
Interleukin-2 (IL-2), the first cytokine that was molecularly cloned, was shown to be a T cell
growth factor essential for the proliferation of T cells and the generation of effector and …
growth factor essential for the proliferation of T cells and the generation of effector and …
Coeliac disease
Coeliac disease is an immune-mediated enteropathy against dietary gluten present in
wheat, rye and barley and is one of the most common lifelong food-related disorders …
wheat, rye and barley and is one of the most common lifelong food-related disorders …
European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease
S Husby, S Koletzko, IR Korponay-Szabó… - Journal of pediatric …, 2012 - journals.lww.com
Objective: Diagnostic criteria for coeliac disease (CD) from the European Society for
Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) were published in …
Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) were published in …
Ectopic lymphoid-like structures in infection, cancer and autoimmunity
Ectopic lymphoid-like structures often develop at sites of inflammation where they influence
the course of infection, autoimmune disease, cancer and transplant rejection. These …
the course of infection, autoimmune disease, cancer and transplant rejection. These …
The Oslo definitions for coeliac disease and related terms
Objective The literature suggests a lack of consensus on the use of terms related to coeliac
disease (CD) and gluten. Design A multidisciplinary task force of 16 physicians from seven …
disease (CD) and gluten. Design A multidisciplinary task force of 16 physicians from seven …
Celiac disease: a review of current concepts in pathogenesis, prevention, and novel therapies
Our understanding of celiac disease and how it develops has evolved significantly over the
last half century. Although traditionally viewed as a pediatric illness characterized by …
last half century. Although traditionally viewed as a pediatric illness characterized by …
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
We performed a genome-wide association study (GWAS) of IgA nephropathy (IgAN), the
most common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals …
most common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals …
Spectrum of gluten-related disorders: consensus on new nomenclature and classification
A decade ago celiac disease was considered extremely rare outside Europe and, therefore,
was almost completely ignored by health care professionals. In only 10 years, key …
was almost completely ignored by health care professionals. In only 10 years, key …
[HTML][HTML] Celiac disease: prevalence, diagnosis, pathogenesis and treatment
N Gujral, HJ Freeman… - World journal of …, 2012 - ncbi.nlm.nih.gov
Celiac disease (CD) is one of the most common diseases, resulting from both environmental
(gluten) and genetic factors [human leukocyte antigen (HLA) and non-HLA genes]. The …
(gluten) and genetic factors [human leukocyte antigen (HLA) and non-HLA genes]. The …
Interleukin-21: a double-edged sword with therapeutic potential
R Spolski, WJ Leonard - Nature reviews Drug discovery, 2014 - nature.com
Interleukin-21 is a cytokine with broad pleiotropic actions that affect the differentiation and
function of lymphoid and myeloid cells. Since its discovery in 2000, a tremendous amount …
function of lymphoid and myeloid cells. Since its discovery in 2000, a tremendous amount …