A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection

DA Jamison Jr, S Anand Narayanan… - European Journal of …, 2022 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has claimed approximately 5 million lives
and 257 million cases reported globally. This virus and disease have significantly affected …

[HTML][HTML] Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity

HM Mengist, AJK Kombe, D Mekonnen, A Abebaw… - Seminars in …, 2021 - Elsevier
Responsible for more than 4.9 million deaths so far, COVID-19, caused by SARS-CoV-2, is
instigating devastating effects on the global health care system whose impacts could be …

Global landscape of SARS-CoV-2 mutations and conserved regions

MH Abbasian, M Mahmanzar, K Rahimian… - Journal of Translational …, 2023 - Springer
Background At the end of December 2019, a novel strain of Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) disease (COVID-19) has been identified in Wuhan …

The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies

S Zhang, L Wang, G Cheng - Molecular therapy, 2022 - cell.com
The SARS-CoV-2 virus, the pathogen causing COVID-19, has caused more than 200 million
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …

SARS-CoV-2 infection: new molecular, phylogenetic, and pathogenetic insights. Efficacy of current vaccines and the potential risk of variants

JC Rotondo, F Martini, M Maritati, C Mazziotta… - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered
coronavirus responsible for the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 …

Predicting the zoonotic capacity of mammals to transmit SARS-CoV-2

IR Fischhoff, AA Castellanos… - … of the Royal …, 2021 - royalsocietypublishing.org
Back and forth transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) between humans and animals will establish wild reservoirs of virus that endanger long …

Phytochemicals-based targeting RdRp and main protease of SARS-CoV-2 using docking and steered molecular dynamic simulation: A promising therapeutic …

A Parihar, ZF Sonia, F Akter, MA Ali, FT Hakim… - Computers in Biology …, 2022 - Elsevier
The ongoing COVID-19 pandemic has affected millions of people worldwide and caused
substantial socio-economic losses. Few successful vaccine candidates have been approved …

COVID-19 vaccines: an overview of different platforms

D Kudlay, A Svistunov - Bioengineering, 2022 - mdpi.com
Vaccination is one of the key strategies to stop the COVID-19 pandemic. This review aims to
evaluate the current state of vaccine development and to determine the issues that merit …

Relaxing restrictions at the pace of vaccination increases freedom and guards against further COVID-19 waves

S Bauer, S Contreras, J Dehning… - PLoS computational …, 2021 - journals.plos.org
Mass vaccination offers a promising exit strategy for the COVID-19 pandemic. However, as
vaccination progresses, demands to lift restrictions increase, despite most of the population …

[HTML][HTML] Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease

RW Cross, ZA Bornholdt, AN Prasad, C Woolsey… - JCI insight, 2022 - ncbi.nlm.nih.gov
A major challenge in managing acute viral infections is ameliorating disease when treatment
is delayed. Previously, we reported the success of a 2-pronged mAb and antiviral remdesivir …