Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

Within the limited antifungal armamentarium, the azole antifungals are the most frequent
class used to treat Candida infections. Azole antifungals such as fluconazole are often …

Candida glabrata is a yeast of increasing medical relevance, particularly in critically ill
patients. It is the second most isolated Candida species associated with invasive candidiasis …

Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

Background. Fluconazole (FLC) resistance is common in C. glabrata and echinocandins are
often used as first-line therapy. Resistance to echinocandin therapy has been associated …

Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …

The longstanding model is that most bloodstream infections (BSIs) are caused by a single
organism. We perform whole genome sequencing of five-to-ten strains from blood culture …

Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and
vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous …

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