Pericytes are known as the mural cells in small-caliber vessels that interact closely with the
endothelium. Pericytes play a key role in vasculature formation and homeostasis, and when …

Cerebral amyloid angiopathy, which is defined by cerebrovascular deposition of amyloid β,
is a common age-related small vessel pathology associated with intracerebral haemorrhage …

The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

Gut microbiota in interaction with intestinal host tissues influences many brain functions and
microbial dysbiosis has been linked with brain disorders, such as neuropsychiatric …

There is increasing evidence for blood–brain barrier (BBB) alterations in Parkinson's
disease (PD), the second most common neurodegenerative disorder with rapidly rising …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with a few FDA-
approved drugs that provide modest symptomatic benefits and only two FDA-approved …

Investigating the genetic underpinnings of human aging is essential for unraveling the
etiology of and develo** actionable therapies for chronic diseases. Here, we characterize …

Blood-CNS barrier disruption is a hallmark of numerous neurological disorders, yet whether
barrier breakdown is sufficient to trigger neurodegenerative disease remains unresolved …

Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive
cyanopeptides in freshwater, marine, and terrestrial ecosystems. The health significance of …