[HTML][HTML] Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies

H Lin, Y Yu, L Zhu, N Lai, L Zhang, Y Guo, X Lin… - Redox Biology, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline

J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …

Characterization of two O-methyltransferases involved in the biosynthesis of O-methylated catechins in tea plant

JQ **, FR Qu, H Huang, QS Liu, MY Wei… - Nature …, 2023 - nature.com
Tea is known for having a high catechin content, with the main component being (−)-
epigallocatechin gallate (EGCG), which has significant bioactivities, including potential anti …

Alzheimer's disease and green tea: epigallocatechin-3-gallate as a modulator of inflammation and oxidative stress

V Valverde-Salazar, D Ruiz-Gabarre… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia, characterised by a
marked decline of both memory and cognition, along with pathophysiological hallmarks …

Extraction, characterization of polyphenols from certain medicinal plants and evaluation of their antioxidant, antitumor, antidiabetic, antimicrobial properties, and …

A Mueed, S Shibli, DA Al-Quwaie, MF Ashkan… - Frontiers in …, 2023 - frontiersin.org
Introduction Dietary medicinal plants are among the most sought-after topics in alternative
medicine today due to their preventive and healing properties against many diseases. Aim …

Neurodegenerative diseases and catechins:(−)-epigallocatechin-3-gallate is a modulator of chronic neuroinflammation and oxidative stress

S Li, Z Wang, G Liu, M Chen - Frontiers in Nutrition, 2024 - frontiersin.org
Catechins, a class of phytochemicals found in various fruits and tea leaves, have garnered
attention for their diverse health-promoting properties, including their potential in combating …

Advances in the anti-atherosclerotic mechanisms of epigallocatechin gallate

Y Liu, Y Long, J Fang, G Liu - Nutrients, 2024 - mdpi.com
Atherosclerosis (AS) is a common clinical sickness and the major pathological basis of
ischemic cardiocerebrovascular diseases (CCVDs). The pathogenesis of AS involves a …

Flavonoids bridging the gut and the brain: Intestinal metabolic fate, and direct or indirect effects of natural supporters against neuroinflammation and …

G Magni, B Riboldi, K Petroni, S Ceruti - Biochemical Pharmacology, 2022 - Elsevier
In recent years, experimental evidence suggested a possible role of the gut microbiota in the
onset and development of several neurodegenerative disorders, such as AD and PD, MS …

[HTML][HTML] Tea-break with epigallocatechin gallate derivatives–Powerful polyphenols of great potential for medicine

P Bakun, DT Mlynarczyk, T Koczorowski… - European Journal of …, 2023 - Elsevier
Epigallocatechin gallate (EGCG) is a polyphenol present in green tea (Camellia sinensis),
which has revealed anti-cancer effects toward a variety of cancer cells in vitro and protective …

The applications of epigallocatechin gallate (EGCG)-nanogold conjugate in cancer therapy

M Karimi-Shahri, A Alalikhan, P Hashemian… - …, 2023 - iopscience.iop.org
Cancer has recently increased the death toll worldwide owing to inadequate therapy and
decreased drug bioavailability. Long-term and untargeted chemotherapeutic exposure …