Genomic analysis has greatly influenced the diagnosis and clinical management of patients
affected by diverse forms of hematologic malignancies. Here, we review how genetic …

Abstract Purpose of Review Immunohistochemistry is an integral technique for tissue-based
diagnostics and biomarker detection with broad worldwide adoption. Advances in core …

Mitogen-activated protein kinases (MAP kinases) are a family of kinases that regulates a
range of biological processes implicated in the response to growth factors like latelet …

Background Treatment options for oncological diseases have been enhanced by the advent
of targeted therapies. The point mutation of the BRAF gene at codon 600 (BRAF V600E) is …

Despite significant progress in the development of treatment options, melanoma remains a
leading cause of death due to skin cancer. Advances in our understanding of the genetic …

Subtypes of automatically maintained self‐injurious behavior (SIB) have been defined
based on response patterns observed during the functional analysis, which are thought to …

Simple Summary Vulvar melanoma (VM) is a rare and fatal disease. Knowledge of this
disease is poor and, consequently, so is knowledge of the prognosis. Our aim was to collect …

Context.—Melanotic schwannoma (MS) is a nerve sheath tumor with a uniform composition
of variably melanin-producing Schwann cells and metastatic potential. The MS is an …

Simple Summary In the past 20 years, the development of targeted therapies that can be
matched to a tumor's molecular and immune abnormalities has resulted in the improvement …

Background: Around 50% of primary melanomas harbour BRAF mutations, but their
prognostic impact has not been clear. Recently, a BRAF-V600E mutation-specific antibody …