Abstract Targeted Recombination in Active Populations (TRAP) represents an effective and
extensively applied technique that has earned significant utilization in neuroscience over the …

The mammalian cortex is comprised of cells classified into types according to shared
properties. Defining the contribution of each cell type to the processes guided by the cortex …

The problem of drug resistance in epilepsy means that in many cases, a surgical treatment
may be advised. But this is only possible if there is an epileptic focus, and resective brain …

We present an enhancer AAV toolbox for accessing and perturbing striatal cell types and
circuits. Best-in-class vectors were curated for accessing major striatal neuron populations …

Thermogenetics is a promising neuromodulation technique based on the use of heat-
sensitive ion channels. However, on the way to its clinical application, a number of questions …

Opioid receptors within the CNS regulate pain sensation and mood and are key targets for
drugs of abuse. Within the adult rodent hippocampus (HPC), μ-opioid receptor agonists …

Cholinergic projection neurons of the nucleus basalis and substantia innominata (NBM/SI)
densely innervate the basolateral amygdala (BLA) and have been shown to contribute to the …

A new study has identified a novel direct–indirect circuit architecture connecting the
striosome compartment of the striatum with midbrain dopamine neurons. This circuit has the …

Curiosity-driven interactions with novel cues in our environment represent a common
behavioral trait across the animal kingdom. Exposure to a novel environment (NE) reshapes …