Benchmarking of alignment-free sequence comparison methods

A Zielezinski, HZ Girgis, G Bernard, CA Leimeister… - Genome biology, 2019 - Springer
Background Alignment-free (AF) sequence comparison is attracting persistent interest driven
by data-intensive applications. Hence, many AF procedures have been proposed in recent …

[HTML][HTML] The SeqAn C++ template library for efficient sequence analysis: A resource for programmers

K Reinert, TH Dadi, M Ehrhardt, H Hauswedell… - Journal of …, 2017 - Elsevier
Background The use of novel algorithmic techniques is pivotal to many important problems
in life science. For example the sequencing of the human genome (Venter et al., 2001) …

MetaProb: accurate metagenomic reads binning based on probabilistic sequence signatures

S Girotto, C Pizzi, M Comin - Bioinformatics, 2016 - academic.oup.com
Motivation Sequencing technologies allow the sequencing of microbial communities directly
from the environment without prior culturing. Taxonomic analysis of microbial communities, a …

K2mem: discovering discriminative k-mers from sequencing data for metagenomic reads classification

D Storato, M Comin - IEEE/ACM Transactions on Computational …, 2021 - ieeexplore.ieee.org
The major problem when analyzing a metagenomic sample is to taxonomically annotate its
reads to identify the species they contain. Most of the methods currently available focus on …

Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy

H Arbel, S Basu, WW Fisher, AS Hammonds… - Proceedings of the …, 2019 - pnas.org
Identifying functional enhancer elements in metazoan systems is a major challenge. Large-
scale validation of enhancers predicted by ENCODE reveal false-positive rates of at least …

MetaCon: unsupervised clustering of metagenomic contigs with probabilistic k-mers statistics and coverage

J Qian, M Comin - BMC bioinformatics, 2019 - Springer
Motivation Sequencing technologies allow the sequencing of microbial communities directly
from the environment without prior culturing. Because assembly typically produces only …

Fast and sensitive classification of short metagenomic reads with skraken

J Qian, D Marchiori, M Comin - … 2017, Porto, Portugal, February 21–23 …, 2018 - Springer
The major problem when analyzing a metagenomic sample is to taxonomically annotate its
reads in order to identify the species and their relative abundances. Many tools have been …

A framework for space-efficient variable-order Markov models

F Cunial, J Alanko, D Belazzougui - Bioinformatics, 2019 - academic.oup.com
Motivation Markov models with contexts of variable length are widely used in bioinformatics
for representing sets of sequences with similar biological properties. When models contain …

Improving metagenomic classification using discriminative k-mers from sequencing data

D Storato, M Comin - … 16th International Symposium, ISBRA 2020, Moscow …, 2020 - Springer
The major problem when analyzing a metagenomic sample is to taxonomically annotate its
reads to identify the species they contain. Most of the methods currently available focus on …

Data-driven smart bike-sharing system by implementing machine learning algorithms

J Qian, M Comin, L Pianura - 2018 Sixth International …, 2018 - ieeexplore.ieee.org
This paper aims to solve a real-life problem: the bike-sharing management system arises the
requirement of offering the customers the accessibility of the bikes in different bike-stations …