The role of the renin angiotensin aldosterone system (RAAS) and the gene variants of its
components in susceptibility to diabetic nephropathy (DN) have been investigated in …

Background Variants of the human genes coding for renin, angiotensin-converting enzyme
(ACE), angiotensinogen (AGT) and the angiotensin II type-I receptor (AT1R) are …

Objective This meta-analysis attempted to derive pooled estimates for the associations
between various cardiovascular-renal disorders and the deletion/insertion (D/I) …

We investigated familial clustering of diabetic retinopathy and nephropathy in the families of
372 subjects from the Diabetes Control and Complications Trial (DCCT). These subjects had …

An insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene
has repeatedly been shown to be associated with ischaemic heart disease, but the …

Aims/hypothesis The ACE insertion/deletion polymorphism has been examined for
association with diabetic nephropathy over the past decade with conflicting results. To clarify …

Objective In this meta-analysis, we attempted to derive pooled estimates for the putative
associations between various cardiovascular–renal disorders and the M235T polymorphism …

We examined whether the ACE gene insertion/deletion (I/D) polymorphism modulates renal
disease progression in IDDM and how ACE inhibitors influence this relationship. The …

Angiotensin-converting enzyme (ACE) I/D genotype and renal ACE gene expression.
Background The angiotensin-converting enzyme (ACE) I/D genotype affects serum ACE …

Introduction: The effect of angiotensin-converting enzyme (ACE) insertion/deletion (I/D)
polymorphism on risk of diabetic nephropathy (DN) is still conflicting. The present meta …