The spermatozoon is a highly differentiated and polarized cell, with two main structures: the
head, containing a haploid nucleus and the acrosomal exocytotic granule, and the flagellum …

Autosomal dominant polycystic kidney disease (ADPKD), with an estimated genetic
prevalence between 1: 400 and 1: 1,000 individuals, is the third most common cause of end …

Recent studies have shown that several members of the G-protein-coupled receptors
(GPCR) superfamily play crucial roles in the maintenance of ion–water homeostasis of the …

Semen quality is one of the most important factors for the success of artificial insemination
which has been widely applied in swine industry to take the advantages of the superior …

Backgrounds and aims As a central event during liver fibrosis, hepatic stellate cells (HSC)
have been thought to be a potential therapeutic target for liver fibrosis. Previous studies …

Taxifolin (TAX), as a natural flavonoid, has been widely focused on due to its strong anti-
oxidation, anti-inflammation, anti-virus, and even anti-tumor activity. However, the effect of …

Mammalian spermatozoa are not mature after ejaculation and must undergo additional
functional and structural changes within female reproductive tracts to achieve subsequent …

Lepidoptera are unusual in possessing two distinct kinds of sperm, regular nucleated
(eupyrene) sperm and anucleate (apyrene) sperm ('parasperm'). Sperm of both types are …

Introduction Alginate oligosaccharide (AOS), as a natural non-toxic plant extract, has been
paid more attention in recent years due to its strong antioxidant, anti-inflammatory, and even …

Plasmodium parasites, the causative agents of malaria, possess a complex lifecycle;
however, the mechanisms of gene regulation involved in the cell-type changes remain …