Many infections of the musculoskeletal system are biofilm infections that develop on non‐
living surfaces. Microorganisms adhere either on dead bone (sequesters) or implants. As a …

Prosthetic joint infection (PJI) is a severe complication after arthroplasty. Its management
combines surgical intervention, whose type depends on the clinical situation, and prolonged …

It is important to know the spectrum of the microbial aetiology of prosthetic joint infections
(PJIs) to guide empiric treatment and establish antimicrobial prophylaxis in joint …

This review article summarizes the recent advances in pathogenic mechanisms and novel
therapeutic strategies for osteomyelitis, covering both periprosthetic joint infections and …

We documented the adjunctive bacteriophage therapy to treat a chronic relapsing
periprosthetic joint infection of the knee and chronic osteomyelitis of the femur caused by …

One or more of the authors of this paper have disclosed potential or pertinent conflicts of
interest, which may include receipt of payment, either direct or indirect, institutional support …

Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

Fracture-related infection (FRI) is a major complication in musculoskeletal trauma and one of
the leading causes of morbidity. Standardization of general treatment strategies for FRI has …

The aim of our study was to characterize the etiology of prosthetic joint infections (PJIs)—
including multidrug-resistant organisms (MDRO)—by category of infection. A multicenter …

Local injection of a bacteriophages mix during debridement, antibiotics and implant
retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic …