Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …

Alzheimer's disease (AD) is the most common form of dementia worldwide, with a complex,
poorly understood pathogenesis. Cerebral atrophy, amyloid-β (Aβ) plaques, and …

Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

The importance of neuroglia in maintaining normal brain function under physiological and
pathological conditions has been supported by growing evidence in recent years. The most …

Alzheimer's disease (AD) is a biologically complex neurodegenerative dementia. Nearly 20
years ago, with the combination of observations from biochemistry, neuropathology and …

Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …

The mitochondrial permeability transition (PT) is a permeability increase of the inner
mitochondrial membrane mediated by a channel, the permeability transition pore (PTP) …

Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …

People with epilepsy—in particular, late-onset epilepsy of unknown aetiology—have an
elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer …