Pharmacogenomics: current status and future perspectives

M Pirmohamed - Nature Reviews Genetics, 2023‏ - nature.com
Inter-individual variability in drug response, be it efficacy or safety, is common and likely to
become an increasing problem globally given the growing elderly population requiring …

Drug-induced liver injury—types and phenotypes

JH Hoofnagle, ES Björnsson - New England Journal of Medicine, 2019‏ - Mass Medical Soc
Drug-Induced Liver Injury The liver has a range of responses to drug-induced injury, with a
number of phenotypes. In addition, idiosyncratic reactions may occur as a consequence of …

[PDF][PDF] Drug allergy: a 2022 practice parameter update

DA Khan, A Banerji, KG Blumenthal, EJ Phillips… - Journal of Allergy and …, 2022‏ - Elsevier
Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

RJ Fontana, I Liou, A Reuben, A Suzuki, MI Fiel… - Hepatology, 2023‏ - journals.lww.com
There are currently more than 1000 prescription medications available for use in the United
States and more than 100,000 over-the-counter herbal and dietary supplements (HDS) …

Drug-induced liver injury: a comprehensive review

T Hosack, D Damry, S Biswas - Therapeutic advances in …, 2023‏ - journals.sagepub.com
Drug-induced liver injury (DILI) remains a challenge in clinical practice and is still a
diagnosis of exclusion. Although it has a low incidence amongst the general population, DILI …

Drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): clinical features and pathogenesis

N Hama, R Abe, A Gibson, EJ Phillips - The Journal of Allergy and Clinical …, 2022‏ - Elsevier
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is one example of a severe delayed T-cell–mediated adverse …

EASL clinical practice guidelines: drug-induced liver injury

RJ Andrade, GP Aithal, ES Björnsson, N Kaplowitz… - Journal of …, 2019‏ - Elsevier
Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver
disorders faced by hepatologists, because of the myriad of drugs used in clinical practice …

Drug induced liver injury: an update

M Garcia-Cortes, M Robles-Diaz, C Stephens… - Archives of …, 2020‏ - Springer
Drug induced liver injury (DILI) is a relatively rare hepatic condition in response to the use of
medications, illegal drugs, herbal products or dietary supplements. It occurs in susceptible …

Incidence and risk factors of drug‐induced liver injury

X Li, J Tang, Y Mao - Liver international, 2022‏ - Wiley Online Library
The epidemiology and aetiology of drug‐induced liver injury (DILI) vary across different
countries and populations. Overall, DILI is rare in the general population but has become …

Drug-induced liver injury: Asia Pacific Association of Study of Liver consensus guidelines

H Devarbhavi, G Aithal, S Treeprasertsuk… - Hepatology …, 2021‏ - Springer
Idiosyncratic drug-induced liver injury mimics acute and chronic liver disease. It is under
recognized and underrecognised because of the lack of pathognomonic diagnostic …