Bcl-2 family proteins

JC Reed - Oncogene, 1998 - nature.com
Bcl-2 family proteins serve as critical regulators of pathways involved in apoptosis, acting to
either inhibit or promote cell death. Altered expression of these proteins occurs commonly in …

[HTML][HTML] Double identity for proteins of the Bcl-2 family

JC Reed - Nature, 1997 - nature.com
Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The
mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic …

Bax directly induces release of cytochrome c from isolated mitochondria

JM Jürgensmeier, Z ** the balance of life and death
LD Walensky - Cell Death & Differentiation, 2006 - nature.com
The discovery of B-cell lymphoma-2 (BCL-2) over 20 years ago revealed a new paradigm in
cancer biology: the development and persistence of cancer can be driven by molecular …

The deadly landscape of pro‐apoptotic BCL‐2 proteins in the outer mitochondrial membrane

MPA Luna‐Vargas, JE Chipuk - The FEBS journal, 2016 - Wiley Online Library
Apoptosis is a biological process that removes damaged, excess or infected cells through a
genetically controlled mechanism. This process plays a crucial role in organismal …