New treatment options in elderly patients with diffuse large B-cell lymphoma

A Arcari, F Cavallo, B Puccini, D Vallisa - Frontiers in Oncology, 2023 - frontiersin.org
Most patients with Diffuse Large B-cell Lymphoma (DLBCL) are old (> 65 years of age) and
this population is expected to increase in the following years. A simplified geriatric …

[HTML][HTML] Cellular therapies in older adults with hematological malignancies: A case-based, state-of-the-art review

NR Neuendorff, A Khan, F Ullrich, S Yates… - Journal of Geriatric …, 2024 - Elsevier
Cellular therapies, including autologous stem cell transplant (ASCT), allogeneic
hematopoietic cell transplantation (alloHCT), and chimeric antigen receptor-(CAR-) T cell …

Cell cycle arrest: A breakthrough in the supportive care of older cancer patients

C Falandry, A List, L Balducci - Journal of the American …, 2023 - Wiley Online Library
Background Age is a major risk factor for the acute and chronic complications of cancer
chemotherapy. The current approach to the prevention of these complications is reactive …

The Role of Geriatric Assessment in the Management of Diffuse Large B-Cell Lymphoma

F Merli, S Pozzi, H Catellani, E Barbieri, S Luminari - Cancers, 2023 - mdpi.com
Simple Summary The treatment choice for an older patient with diffuse large B-cell
lymphoma (DLBCL) is challenging due to the complexity of the patient. Among the several …

Long‐term efficacy in patients with relapsed/refractory diffuse large B‐cell lymphoma achieving a complete response with pixantrone

E Cencini, M Rocco, F Ghio, F Simonetti… - European Journal of …, 2023 - Wiley Online Library
Introduction The prognosis of diffuse large B‐cell lymphoma (DLBCL) patients with refractory
or multiply relapsed (R/R) disease is disappointing. Pixantrone is currently approved as third …

Validation and modification of simplified Geriatric Assessment and Elderly Prognostic Index: Effective tools for older patients with diffuse large B‐cell lymphoma

X Yun, J Bai, R Feng, J Li, T Wang, Y Yang… - Cancer …, 2024 - Wiley Online Library
Geriatric assessment can aid in optimizing treatment strategies and supportive interventions
for older patients with diffuse large B‐cell lymphoma (DLBCL). Fondazione Italiana Linformi …

Curative intent therapy for DLBCL in the elderly

A Tucci, L Masina, S Luminari - Leukemia & Lymphoma, 2024 - Taylor & Francis
Older patients with aggressive lymphoma are extremely heterogeneous due to the high
frequency of functional limitations and comorbidities and to the different biological profiles …

The Haemato‐Oncology Frailty (HOF) score to assess frailty in lymphoma

H Ramdany, T Lofaro, S Deplano - European Journal of …, 2024 - Wiley Online Library
Morbidity and mortality during chemotherapy in older adults with haematological malignancy
can be unpredictable. The Haemato‐Oncology Frailty (HOF) score was previously found to …

Appropriate Treatment Intensity for Diffuse Large B-Cell Lymphoma in the Older Population: A Review of the Literature

S Yamasaki - Hematology Reports, 2024 - mdpi.com
Most patients with diffuse large B-cell lymphoma (DLBCL) are> 65 years of age, with the
number of patients expected to increase in the coming years. A comprehensive geriatric …

Therapeutic approach to patients with early stage diffuse large B cell lymphoma: retrospective, multicenter, real-life study of the 'RTL'(regional Tuscan lymphoma …

E Cencini, M Palazzo, D Dardanis… - Leukemia & …, 2025 - Taylor & Francis
Abstract Treatment strategies for early stage diffuse large B-cell lymphoma (ES-DLBCL)
include R-CHOP, with a similar schedule to that used in advanced stage, or a reduced …