Spiders are a source of intrigue and fear, and several myths exist about their medical effects.
Many people believe that bites from various spider species cause necrotic ulceration …

The Loxosceles genus spiders (the brown spiders) are encountered in all the continents,
and the clinical manifestations following spider bites include skin necrosis with gravitational …

Venomous animals use their venoms as tools for defense or predation. These venoms are
complex mixtures, mainly enriched of proteic toxins or peptides with several, and different …

Loxosceles spiders are found globally, especially in South and North America. In Brazil,
approximately 10,000 cases of Loxosceles spp. spider bites are reported annually. Herein …

Brown spiders are venomous arthropods that use their venom for predation and defense. In
humans, bites of these animals provoke injuries including dermonecrosis with gravitational …

Brown spider envenomation results in dermonecrosis with gravitational spreading
characterized by a marked inflammatory reaction and with lower prevalence of systemic …

Loxosceles venom comprises a mixture of diverse toxins that induces intense local
inflammatory reaction, dermonecrotic injury, platelet aggregation, hemolytic anemia and …

Cutaneous loxoscelism envenomation by Loxosceles spiders is characterized by the
development of a dermonecrotic lesion, strong inflammatory response, the production of pro …

Spiders of Loxosceles genus are widely distributed and their venoms contain
phospholipases D (PLDs), which degrade phospholipids and trigger inflammatory …

Abstract Loxosceles spp.(Araneae, Sicariidae), known as brown spiders, are distributed in
temperate and tropical regions worldwide. Accidents caused by these spiders are known as …