Diabetic kidney disease

MC Thomas, M Brownlee, K Susztak… - Nature reviews Disease …, 2015 - nature.com
The kidney is arguably the most important target of microvascular damage in diabetes. A
substantial proportion of individuals with diabetes will develop kidney disease owing to their …

Chalcones and their therapeutic targets for the management of diabetes: Structural and pharmacological perspectives

DK Mahapatra, V Asati, SK Bharti - European journal of medicinal chemistry, 2015 - Elsevier
Diabetes Mellitus (DM) is the fastest growing metabolic disorder affecting about 387 million
people across the globe and is estimated to affect 592 million people by year 2030. The …

Sanziguben polysaccharides improve diabetic nephropathy in mice by regulating gut microbiota to inhibit the TLR4/NF-κB/NLRP3 signalling pathway

F Wang, C Liu, LZ Ren, YY Li, HM Yang… - Pharmaceutical …, 2023 - Taylor & Francis
Context Sanziguben (SZGB) is an empirical prescription used in traditional Chinese
medicine to treat diabetic nephropathy (DN). As an abundant and primarily effective …

Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation

C Wang, Y Pan, QY Zhang, FM Wang, LD Kong - PloS one, 2012 - journals.plos.org
Hyperuricemia, hyperlipidemia and inflammation are associated with diabetic nephropathy.
The NLRP3 inflammasome-mediated inflammation is recently recognized in the …

Prevalence and risk factors of diabetic nephropathy in an urban South Indian population: the Chennai Urban Rural Epidemiology Study (CURES 45)

R Unnikrishnan, M Rema, R Pradeepa… - Diabetes …, 2007 - diabetesjournals.org
OBJECTIVE—The aim of this study was to determine the prevalence of diabetic nephropathy
among urban Asian-Indian type 2 diabetic subjects. RESEARCH DESIGN AND METHODS …

A systematic literature review of sport and physical activity participation in culturally and linguistically diverse (CALD) migrant populations

T O'Driscoll, LK Banting, E Borkoles, R Eime… - Journal of immigrant and …, 2014 - Springer
Culturally and linguistically diverse (CALD) migrants face significant health risks as they
adapt to new cultures. These risks are exacerbated by their limited participation in …

Prevention of diabetic nephropathy in Ins2+/−AkitaJ mice by the mitochondria-targeted therapy MitoQ

BK Chacko, C Reily, A Srivastava… - Biochemical …, 2010 - portlandpress.com
Mitochondrial production of ROS (reactive oxygen species) is thought to be associated with
the cellular damage resulting from chronic exposure to high glucose in long-term diabetic …

Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study

RC Slieker, AAWA van der Heijden, MK Siddiqui… - bmj, 2021 - bmj.com
Objectives To identify and assess the quality and accuracy of prognostic models for
nephropathy and to validate these models in external cohorts of people with type 2 diabetes …

Bioactive compounds from Cornus officinalis fruits and their effects on diabetic nephropathy

W Ma, KJ Wang, CS Cheng, G Yan, WL Lu… - Journal of …, 2014 - Elsevier
Ethnoparmacological relevance The fruit of Cornus officinalis, called “Shanzhuyu”, a
traditional medicine in China, is used for the treatment of kidney diseases, including diabetic …

Diabetic nephropathy: A twisted thread to unravel

N Dagar, P Das, P Bisht, AK Taraphdar, R Velayutham… - Life sciences, 2021 - Elsevier
Diabetic nephropathy (DN), a persistent microvascular problem of diabetes mellitus is
described as an elevated level of albumin excretion in urine and impaired renal activity. The …