Label‐Free Assessment of Key Biological Autofluorophores: Material Characteristics and Opportunities for Clinical Applications
JM Campbell, M Gosnell, A Agha, S Handley… - Advanced …, 2024 - Wiley Online Library
Autofluorophores are endogenous fluorescent compounds that naturally occur in the intra
and extracellular spaces of all tissues and organs. Most have vital biological functions–like …
and extracellular spaces of all tissues and organs. Most have vital biological functions–like …
Clinical applications of non‐invasive multi and hyperspectral imaging of cell and tissue autofluorescence beyond oncology
Hyperspectral and multispectral imaging of cell and tissue autofluorescence employs
fluorescence imaging, without exogenous fluorophores, across multiple excitation/emission …
fluorescence imaging, without exogenous fluorophores, across multiple excitation/emission …
Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo
STUDY QUESTION Can label-free, non-invasive optical imaging by hyperspectral
autofluorescence microscopy discern between euploid and aneuploid cells within the inner …
autofluorescence microscopy discern between euploid and aneuploid cells within the inner …
Pancreatic Islet Viability Assessment Using Hyperspectral Imaging of Autofluorescence
Islets prepared for transplantation into type 1 diabetes patients are exposed to
compromising intrinsic and extrinsic factors that contribute to early graft failure, necessitating …
compromising intrinsic and extrinsic factors that contribute to early graft failure, necessitating …
Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes
Increasing age has a major detrimental impact on female fertility, which, with an ageing
population, has major sociological implications. This impact is primarily mediated through …
population, has major sociological implications. This impact is primarily mediated through …
Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features
Optimally preserved urinary exfoliated renal proximal tubule cells were assessed by
multispectral imaging of cell autofluorescence. We demonstrated different multispectral …
multispectral imaging of cell autofluorescence. We demonstrated different multispectral …
Emerging clinical applications in oncology for non‐invasive multi‐and hyperspectral imaging of cell and tissue autofluorescence
Hyperspectral and multispectral imaging of cell and tissue autofluorescence is an emerging
technology in which fluorescence imaging is applied to biological materials across multiple …
technology in which fluorescence imaging is applied to biological materials across multiple …
Pterygium and ocular surface squamous neoplasia: optical biopsy using a novel autofluorescence multispectral imaging technique
Simple Summary Cancer is able to damage the surface of the eye, especially in countries
like Australia with high exposure to ultraviolet radiation from the sun. Such cancer (ocular …
like Australia with high exposure to ultraviolet radiation from the sun. Such cancer (ocular …
Exfoliated kidney cells from urine for early diagnosis and prognostication of CKD: The way of the future?
Chronic kidney disease (CKD) is a global health issue, affecting more than 10% of the
worldwide population. The current approach for formal diagnosis and prognostication of …
worldwide population. The current approach for formal diagnosis and prognostication of …
Metabolic light absorption, scattering, and emission (MetaLASE) microscopy
Optical imaging of metabolism can provide key information about health and disease
progression in cells and tissues; however, current methods have lacked gold-standard …
progression in cells and tissues; however, current methods have lacked gold-standard …